Clinical Chemistry Controls
Cayman Chemical L-HomocysteIn 10mg
A thiol-containing amino acid; elevated levels lead to HHcy, which is associated with an increased risk of cardiovascular disease and stroke
Cayman Chemical H4 PosItIve Control 12.5nmol
A PROTAC that drives FAK degradation binds to the FAK kinase domain (IC50 15.8 nM) and induces FAK degradation in A549 cells (DC50 1.3 nM) inhibits A549 cell migration and invasion at 100 nM reduces hepatic FAK levels in mice at 8 mg/kg
Biotium Catenin, gamma (Cardiomyocyte Marker) (CTNG/1664), CF647 conjugate, 0.1mg/mL
Gamma catenin, also known as JUP or junction plakoglobin, is a member of the catenin family. The catenins (alpha, beta, gamma, and delta) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion, including adherens junctions.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Catenin, gamma (Cardiomyocyte Marker)(CTNG/2155R), CF647 conjugate, 0.1mg/mL
Gamma catenin, also known as JUP or junction plakoglobin, is a member of the catenin family. The catenins (alpha, beta, gamma, and delta) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion, including adherens junctions. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Catenin, gamma (Cardiomyocyte Marker)(CTNG/2155R), CF740 conjugate, 0.1mg/mL
Gamma catenin, also known as JUP or junction plakoglobin, is a member of the catenin family. The catenins (alpha, beta, gamma, and delta) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion, including adherens junctions. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
AdipoGen Digoxin
Chemical. CAS 20830-75-5. Formula C41H64O14. MW 780.94. Synthetic. Cardiac glycoside from the leaves of Digitalis lanata. It is used to treat cardiac arrhythmias. It is often used as a model substrate of P-glycoprotein Pgp 0.01-10µM and an inhibitor of Na/K-ATPase. Inhibits membrane-bound alpha-subunits of the Na/K ATPase pump in myocytes. The primary mechanism of action involves inhibition of the Na/K ATPase, mainly in the myocardium. This inhibition causes an increase in intracellular sodium levels, resulting in a reversal of the action of the sodium-calcium exchanger, which causes an increase in the intracellular calcium concentration. This leads to a decrease in heart rate and increased storage of calcium in the sarcoplasmic reticulum, causing a corresponding increase in the release of calcium during each action potential.
ABclonal Technology Ferritin Heavy Chain Rabbit
This gene encodes the heavy subunit of ferritin the major intracellular iron storage protein in prokaryotes and eukaryotes It is composed of 24 subunits of the heavy and light ferritin chains Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues A major function of ferritin is the storage of iron in a soluble and nontoxic state Defects in ferritin proteins are associated with several neurodegenerative diseases This gene has multiple pseudogenes Several alternatively spliced transcript variants have been observed but their biological validity has not been determined
Cayman Chemical 7a-hydroxy Cholesterol 10mg
An oxysterol and a precursor in the biosynthesis of CA and CDCA; formed via the oxidation of cholesterol by CYP7A1 in rat liver microsomes; increases ICAM-1, VCAM-1, and E-selectin levels in HUVECs at 40 µM; increases secretion of CCL2 and MMP-9 in serum-deprived THP-1 cells at 5 UG/ml; has been found in macrophages isolated from atherosclerotic lesions in rabbits fed a high-cholesterol diet
