Clinical Chemistry Controls
Cayman Chemical 7-keto Cholesterol 100mg
A bioactive oxysterol; a major oxysterol component of oxidized LDL; produced by oxidation of cholesterol via ethanol-mediated lipid peroxidation or photodamage as well as oxidation of 7-dehydro cholesterol by CYP7A1; inhibits CYP7A1 (IC50 = ~1 μM); induces activation and chemotaxis of retinal microglia as well as polarization to a pro-inflammatory state; increases ocular levels of VEGF, IL-1β, and GRO/KC, macrophage infiltration, and neovascularization in rat eye; levels are increased in lipid deposits in a variety of chronic diseases
Cayman Chemical FerrItIn PROTAC DeFer-2 10mg
A PROTAC that drives ferritin degradation; induces ferritin degradation in B16/F10 cells at 0.5 µM; increases intracellular levels of free iron and induces pyroptosis in B16/F10 cells at 5 µM; ferritin PROTAC DeFer-2 encapsulated in albumin nanoparticles reduces tumor growth and increases survival in a B16/F10 murine melanoma model at 10 mg/kg
Cayman Chemical NAG-thIazolIn 10mg
An OGA inhibitor (Ki = 180 nM); active against V. campbellii (MIC = 0.5 µM)
ABclonal Technology Apolipoprotein CI Rabbit mAb
This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Roche Diagnostics Control E Level 2 Bio, Control reagent for the Cedex Bio and Cedex Bio HT Analyzers, 6 x 0.5mL
Ethanol control solution. This product is intended for quality control by monitoring accuracy and precision of quantitative tests on the Cedex Bio and Cedex Bio HT Analyzers. Control E Level 2 Bio provides an ethanol concentration in the lower part of the measuring range of the ethanol test (ETOHB).
ABclonal Technology Apolipoprotein A1/APOA1
This gene encodes apolipoprotein A-I which is the major protein component of high density lipoprotein (HDL) in plasma The encoded preproprotein is proteolytically processed to generate the mature protein which promotes cholesterol efflux from tissues to the liver for excretion and is a cofactor for lecithin cholesterolacyltransferase (LCAT) an enzyme responsible for the formation of most plasma cholesteryl esters This gene is closely linked with two other apolipoprotein genes on chromosome 11 Defects in this gene are associated with HDL deficiencies including Tangier disease and with systemic non-neuropathic amyloidosis Alternative splicing results in multiple transcript variants at least one of which encodes a preproprotein
Sigma Aldrich Fine Chemicals Biosciences APOLIPOPROTEIN B FROM HUMAN PL
NC2948050 APOLIPOPROTEIN B FROM HUMAN PL
Cayman Chemical DL-HomocysteIn thIolacton 250g
A derivative of DL-homocysteine; inhibits the growth of B. campestris, L. sativa, and E. utilis roots at 50 µM; decreases the maximum rate of left ventricular developed pressure, systolic left ventricular pressure, and coronary flow in isolated rat hearts at 10 µM; induces arteriosclerotic plaque formation in rabbits at 30 mg/kg for eight weeks; has also been used as a precursor in the synthesis of thiolactone-containing monomers for use in polymer-based formaldehyde-scavenging coatings
Cayman Chemical NAG-thIazolIn 50mg
An OGA inhibitor (Ki = 180 nM); active against V. campbellii (MIC = 0.5 µM)