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The V-PLEX SARS-CoV-2 Panel 33 Kit by Meso Scale Diagnostics is a serology test that detects antibodies to SARS-CoV-2 in serum and plasma samples It uses electrochemiluminescence technology and provides quantitative results for IgG antibodies to the spike and nucleocapsid proteins The test has high sensitivity and specificity and has received FDA Emergency Use Authorization It requires the MESO QuickPlex SQ 120 instrument and takes approximately 3 hours to run The kit includes a plate coated with antigens detection antibodies calibrators controls diluent and wash buffer It is intended for use in clinical labs and requires venipuncture whole blood samples
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The V-PLEX Human IL-17D Kit from Meso Scale Discovery is a sandwich immunoassay that allows for the quantitative measurement of human interleukin 17D (IL-17D) in cell culture supernatants serum plasma and other biological fluids The assay utilizes electrochemiluminescence for high sensitivity and a broad dynamic range The kit includes a 96-well plate coated with a capture antibody specific for human IL-17D a detection antibody conjugated to an electrochemiluminescent label and calibrator diluent The assay has high sensitivity with a lower limit of detection of 0 10 pg/mL and an upper limit of quantitation of 1500 pg/mL for cell culture supernatants
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The Mesoscale K15695U-2 is a high-performance thermoelectric module for cooling heating and temperature control It features 127 Bismuth Telluride thermocouples between ceramic substrates With a max operating temperature of 200 C it offers a heat pumping capacity of 15 2W at a hot side of 50 C and cold side of 25 C Key features include a compact size of 40 x 40 x 3 4mm no moving parts for quiet operation and RoHS compliance Suitable for scientific instruments photonics laser systems and food cooling
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The V-PLEX Mouse Cytokine 30-Plex Kit from Meso Scale Discovery is a multiplex immunoassay for measuring 30 mouse cytokines and chemokines in one well It uses electrochemiluminescence detection for high sensitivity and broad dynamic range with low sample volume The kit includes a 96-well plate with capture antibodies detection antibodies labeled with an electrochemiluminescent compound and calibrator solutions for 30 analytes like IL-1 IL-2 IL-6 IFN- TNF- and more providing quantitative results from a small sample
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A σ receptor ligand with anticancer and antiviral activites binds to σ1 and σ2 receptors (Kis 13 and 0.28 nM respectively in MCF-7 cell membranes) selective for σ1 and σ2 receptors over hERG channels (Ki 1000 nM) inhibits growth of MCF-7 and multidrug-resistant MCF-7/adr cells (IC50s 25 and 15 nM respectively) decreases basal P-gp levels in the same cells reduces SARS-CoV-2 infectivity in Vero E6 cells (IC90 278 nM)
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The Human hepatitis B virus e antigen (HBeAg) ELISA kit is used for qualitative identification of HBeAg in human serum and plasma. It employs the qualitative enzyme immunoassay technique. The microtiter plate has been pre-coated with HBeAb. Samples or standards are pipetted into the wells with HRP-conjugated HBeAb. Following a wash to remove any unbound reagent, the TMB substrate solution is added to the wells and color develops in proportion to the amount of HBeAg bound in the initial step. The color development is stopped and the intensity of the color is measured by a microplate reader at 450 nm. It indicates the presence of HBeAg if the O.D. (optical density) of HBeAg is greater than or equal to the cutoff value (2.1× Average O.D. value of negative control). There is no HBeAg present in the sample if the O.D. is less than the cutoff value. One kit contains 96 wells.
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The Meso Scale Diagnostics COVID-19 Respiratory Panel 2 IgG Assay Kit is an in vitro diagnostic test for detecting IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence technology to provide quantitative results for IgG antibodies specific to the SARS-CoV-2 spike and nucleocapsid proteins The test helps identify individuals with an adaptive immune response indicating recent or prior infection Results are positive negative or equivocal It is authorized for emergency use by the FDA under an EUA for authorized labs
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The Meso Scale Discovery V-PLEX Human IL-6 Kit is a multiplex immunoassay that measures levels of human interleukin-6 (IL-6) in serum plasma and cell culture supernatants This assay utilizes electrochemiluminescent detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an electrochemiluminescent compound calibrators controls 10X diluent read buffer wash buffer and plate seals This assay has high specificity and shows minimal cross-reactivity The kit has a detection range of 0 06-1500 pg/mL and requires 25 L of sample per well
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The Meso Scale Discovery V-PLEX Mouse IL-27p28/IL-30 Kit is used to quantitatively measure IL-27p28 and IL-30 in mouse serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This multiplex assay kit includes a plate coated with capture antibodies detection antibodies labeled with an ECL tag and calibrator and control samples It allows concurrent measurement of IL-27p28 and IL-30 from a single sample in as little as 3 5 hours
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The Meso Scale Diagnostics COVID-19 Coronavirus Panel 2 IgG is an in vitro diagnostic test kit that detects IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence technology on Meso Scale Diagnostics proprietary MULTI-ARRAY platform The test kit includes a 96-well plate coated with SARS-CoV-2 antigens detection antibodies calibrators and controls It has 99 6% PPA and 99 6% NPA versus PCR and takes under 3 hours to run The test is CE marked and available for in vitro diagnostic use in countries recognizing the CE mark
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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 31 Mouse IgG Kit is an electrochemiluminescence immunoassay for detecting IgG antibodies to SARS-CoV-2 in mouse serum and plasma It measures antibodies to the spike protein receptor binding domain and nucleocapsid protein using a multiplex format The kit includes a plate with antigens detection antibodies calibrators controls diluent read buffer and wash buffer The 3 5-hour protocol provides quantitative results for SARS-CoV-2 IgG levels enabling researchers to evaluate the humoral immune response and measure neutralizing antibodies in mouse models
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The Meso Scale Discovery SARS-CoV-2 384 Panel 1 IgG is an immunoassay panel that tests for IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence detection technology and provides quantitative results for IgG antibodies to the SARS-CoV-2 spike protein receptor binding domain and nucleocapsid protein The panel allows high-throughput testing with 384-well plates It has high sensitivity and specificity and has received FDA Emergency Use Authorization The panel aids in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection
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