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RdRP-IN-2 is a small-molecule research compound that inhibits RNA-dependent RNA polymerase (RdRp) and shows antiviral activity against SARS-CoV-2 in cell-based assays.
Inhibits RdRp with reported IC50 of 41.2 μM.
Demonstrates antiviral activity in Vero cells (EC50 = 527.3 nM).
High chemical purity (98.0%).
Molecular formula C33H30N2O5S; molar mass 566.67 g·mol⁻¹.
Soluble in DMSO; offered as solid and as a 10 mM solution in DMSO.
For research use only; not for human or clinical use.
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The S-PLEX SARS-CoV-2 N Kit is a multiplex immunoassay panel for the simultaneous qualitative detection of nucleocapsid protein antigens from SARS-CoV-2 in human serum plasma and saliva This assay uses electrochemiluminescence (ECL) on the SECTOR Imager 2400 platform The kit includes a plate coated with capture antibodies detection antibodies conjugated to ruthenium and calibrators and controls needed to run the assay Results are obtained in under 3 hours This assay allows sensitive high-throughput testing for SARS-CoV-2 antigens
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The Meso Scale Diagnostics SARS-CoV-2 Panel 2 IgM is an in vitro diagnostic test for the qualitative detection of IgM antibodies to SARS-CoV-2 in human serum and plasma This electrochemiluminescence immunoassay utilizes a recombinant SARS-CoV-2 nucleocapsid antigen to detect IgM antibodies that are generated by the immune system in response to a SARS-CoV-2 infection The test is intended for use as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection It has not been FDA cleared or approved and has been authorized by FDA under an EUA for use by authorized laboratories
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A set of SARS-CoV-2 neutralizing antibody human plasma controls containing negative control plasma, as well as positive control plasma spiked with low, mid, and high levels of recombinant human anti-SARS-CoV-2 neutralizing IgG antibody
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A DNA sequence encoding the glycoprotein G extracellular domain (Asn 66-Arg 297) of human respiratory syncytial virus A (95 % homologous with strain rsb1734) (P27022-1) was expressed, with a C-terminal polyhistidine tag.
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A DNA sequence encoding the SARS-CoV-2 (2019-nCoV) Spike Protein (RBD) (YP_009724390.1) (Arg319-Phe541) was expressed with a polyhistidine tag at the C-terminus.
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The Meso Scale Discovery Phospho (Ser473)/Total Akt Whole Cell Lysate Kit is designed to measure endogenous levels of Akt and phosphorylated Akt (Ser473) in whole cell lysates The kit includes a 96-well plate coated with capture antibodies against total Akt and phospho-Akt (Ser473) It also includes detection antibodies and buffers needed to perform the assay Results are obtained in as little as 3 5 hours using an electrochemiluminescence plate reader This kit allows for the sensitive reproducible quantification of Akt phosphorylation and activation state in cells It is suitable for studying Akt signaling and screening compounds that modulate Akt phosphorylation
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The Meso Scale Discovery V-PLEX Human IL-6 Kit is a multiplex immunoassay that measures levels of human interleukin 6 (IL-6) in serum plasma and cell culture supernatants This 4-plex assay uses electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with MSD SULFO-TAG calibrators and controls Recommended sample diluent and wash buffer are sold separately This assay has high specificity and less than 0 3% cross-reactivity with other cytokines
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An RSV inhibitor that demonstrates antiviral activity with an EC50 value of 1.4 nM; interferes directly with RSV fusion (EC50 = 5.4 nM), binding to the viral F protein
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Influenza A virus (H3N2) strain A/Baltimore/JH-335/2022 (ATCC VR-3398) is a characterized H3N2 influenza A isolate supplied as a frozen viral culture propagated in MDCK-SIAT1 cells. It is intended for research use in virology studies, vaccine research, antigenic characterization, and assay development.
Characterized H3N2 influenza A strain suitable for research applications.
Supplied as a frozen viral culture propagated in MDCK-SIAT1 cells.
Suitable for virology, vaccine research, and assay development.
Genomic sequence data available via ATCC Genome Portal.
Includes images showing host cell effects.
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