Lipid Controls
Cayman Chemical DLIn-MC2-DMA 10mg
An ionizable cationic lipid; has been used in the formation of LNPs; LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding FVII reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg)
Medchemexpress LLC HY-134781 5mg , CKK-E12 CAS:1432494-65-9 Purity:>98%
HY-134781 5mg CKK-E12 CAS: 1432494-65-9 CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. cKK-E12 was highly selective toward liver parenchymal cell in vivo, Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Kyfora Bio DPTAP 25 MG
DPTAP Chloride (1,2-dipalmitoyl-3-trimethylammonium-propane Chloride) is a cationic lipid and an analogue of DOTAP. It can be used in the formation of liposomes and microbubbles that encapsulate nucleic acids, such as miRNA, as an efficient gene delivery system.Key application(s): Gene delivery, miRNA delivery
Apexbio Technology LLC DSPE-PEG2000-NH₂ 474922-26-4 100mg
DSPE-PEG2000-NH2 (CAS 474922-26-4) is an amphiphilic polymer conjugate composed of 1 2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) and polyethylene glycol (PEG MW 2000 Da) terminating in a primary amine The compound is designed for covalent coupling to biomolecules through its amine functional group enabling surface modification of lipid-based nanoparticles including liposomes and lipid nanoparticles DSPE-PEG2000-NH2 acts primarily by enabling conjugation of peptides proteins antibodies or nucleic acids to nanoparticle surfaces via stable amide bond formation with accessible carboxyl groups Based on these characteristics DSPE-PEG2000-NH2 holds research potential in targeted drug delivery nucleic acid delivery and nanoparticle surface modification in biomedical and pharmaceutical applications
Cayman Chemical DLIn-MC3-DMA 100mg
An ionizable cationic lipid (apparent pKa = 6.44); has been used in the generation of lipid nanoparticles (LNPs) encapsulating siRNA, mRNA, or plasmid DNA for use in vitro and in vivo; LNPs containing DLin-MC3-DMA accumulate in the muscle and non-draining lymph nodes after intramuscular administration and in the spleen after intravenous administration in mice; LNPs containing DLin-MC3-DMA and encapsulating F7 siRNA reduce hepatic and plasma Factor VII levels in mice without inducing liver toxicity
![Avanti Polar Lipids 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt), 474922-77-5, MFCD02262268, 25 mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00037649-C2618-200UL.PNG-250.jpg)
Avanti Polar Lipids 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt), 474922-77-5, MFCD02262268, 25 mg
Formula Weight: 2805.497, Purity >99%, Storage Temperature: -20°C. PEG-modified lipids are typically added to phospholipid vesicles used for drug delivery to provide a steric coating on the surface of the membrane to hinder clearing of the particles by the reticuloendothelial system (RES). This prolongs the circulating plasma half-life of the drug. The plasma half-life of the drug can be "tuned" from several hours to days depending on the size of the PEG and fatty acids attached to the lipid anchor.
Sigma Aldrich Fine Chemicals Biosciences Lipid A monophosphoryl fro1MG
Lipid A monophosphoryl fro1MG
Cayman Chemical DLIn-MC2-DMA 25mg
An ionizable cationic lipid; has been used in the formation of LNPs; LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding FVII reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg)
![Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[PDP(PEG)-2000] (ammonium salt) | 474922-24-2 | >99.0% | C140H273N4O55PS2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259154.png-250.jpg)
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[PDP(PEG)-2000] (ammonium salt) | 474922-24-2 | >99.0% | C140H273N4O55PS2 | 10MG
DSPE-PEG(2000) PDP is an orthopyridyl-disulfide functionalized PEGylated phospholipid (ammonium salt) used to introduce a reducible disulfide linker for bioconjugation and surface functionalization of liposomes and nanoparticles. It is supplied as a purified solid intended for cold storage and long-term stability.
- Orthopyridyl-disulfide functionality enables thiol-reactive conjugation.
- PEG2000 spacer provides steric stabilization and surface shielding.
- Suitable for liposome and nanoparticle surface modification.
- High purity supports reliable and reproducible conjugation chemistry.
- Supplied as a stable solid for cold storage and handling.
- Enables formation of reducible disulfide linkers for controlled release strategies.
Cayman Chemical DLIn-MC4-DMA 50mg
An ionizable cationic lipid (pKa = 6.93); LNPs containing DLin-MC4-DMA and encapsulating siRNA for F7 reduce its gene expression levels in mice