Living Organisms
Sigma Aldrich Fine Chemicals Biosciences Hirudin from leeches lyoph
Hirudin is a 7 kDa acidic protein containing 65 amino acid residues that has an isoelectric point of 3.5-4.0. It is not glycosylated and lacks tryptophan arginine and methionine residues. It is chemically stable between pH 2-12 and at temperatures up to 80C.
Cayman Chemical A943931hydrochLRIde hydra 1mg
A histamine H4 receptor antagonist (Ki = 3.8 nM); inhibits clobenpropit-induced scratching in mice (ED50 = 26 µmoles/kg, i.p.)
Medchemexpress LLC ANTS | 5398-34-5 | 99.1% | 50 MG
ANTS is a fluorescent dye (Excitation wavelength: 380 nm; Emission wavelength: 520 nm). When encapsulated in liposomes with DPX, ANTS can be an effective approach for measuring membrane leakage. It is suitable for high-speed applications in laboratory centrifugation and storage.
- Fluorescent dye for cell staining analysis
- Excitation wavelength of 350 nm
- Emission wavelength of 515 nm
- White to off-white solid appearance
- Purity of 99.09%
- Can be used for membrane leakage measurements
Cayman Chemical Harmalol hydrochloride hydra
A β-carboline alkaloid and an active metabolite of harmaline; an inhibitor of DYRK1A (IC50 = 0.63 µM); an inhibitor of MAO-A (IC50 = 0.66 µM); selective for DYRK1A over Cdk1, Cdk5, CK1α1, Clk4, DYRK2, Pim-1, and GSK3β but also inhibits DYRK1B and Clk1 at 10 µM; inhibits proliferation of H4 human glioblastoma cells (IC50s = 23.7 µM); reduces TCDD-induced increases in CYP1A1 levels in HepG2 cells and prevents TCDD-induced activation of AhR in guinea pig hepatic cytosolic extracts; reduces glutamate-induced cytotoxicity, cytochrome c release, caspase-3 activation, and ROS production in PC12 cells at 25 µM
Cayman Chemical DoxapramhydroCLOrID hydra 10mg
A central respiratory stimulant; increases respiration and phrenic nerve activity in anesthetized cats at a dose of 1.0 mg/kg; acts through carotid chemoreceptors, lacking activity in anesthetized cats following carotid denervation
FOCUS BIOMOLECULES Biochemical Reagents, Domoic acid, Marine natural product neurotoxin, CAS 14277-97-5, 98% by HPLC/NMR (Conforms)
Biochemical Reagents, Domoic acid, Marine natural product neurotoxin, CAS 14277-97-5, 98% by HPLC/NMR (Conforms), Kainic acid-type neurotoxin produced by certain species of the marine pennate diatom Pseudo-nitzschia, is responsible for amnesic shellfish poisoning.1 Suspension feeders such as bivalve mollusks can accumulate and retain high amounts of DA in their tissues, threatening human health.2,3 DA is a potent agonist at kainate and AMPA receptors4 and induces convulsive behavior and seizures in rodents5. It induces structural and molecular changes in the developing zebra fish nervous system.6
Cayman Chemical BIX01294hydroCLOrID hydra 50mg
A selective inhibitor of G9a histone methyltransferase (IC50 = 1.7 μM); less effectively inhibits G9a-like protein (GLP; IC50 = 38 μM) and has no effect on other known histone methyltransferases
Cayman Chemical A943931hydrochLRIde hydra 5mg
A histamine H4 receptor antagonist (Ki = 3.8 nM); inhibits clobenpropit-induced scratching in mice (ED50 = 26 µmoles/kg, i.p.)
Cayman Chemical LTyrosInsodIum salt hydra 250g
A conditionally essential amino acid; a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones; plasma, skeletal muscle, and erythrocyte levels are decreased in patients with chronic kidney disease