Living Organisms
Cayman Chemical FungI Lachnon A 2.5mg
A fungal metabolite; inactive against P. falciparum, C. albicans, and M. tuberculosis; not cytotoxic to KB or BC-1 cells
Escherichia coli (Migula) Castellani and Chalmers - ATCC BAA-3303, drug-resistant bacterial strain (frozen vial)
Escherichia coli clinically derived strain isolated from a human pancreas in 2014. The strain is genome sequenced and characterized for multiple antimicrobial resistance determinants; it is supplied frozen and must be handled under BSL-2 laboratory conditions. Common uses include antimicrobial resistance research, molecular assay development, and antimicrobial drug discovery.
- Clinically derived, isolated from human pancreas in 2014.
- Genome sequenced and annotated for multiple resistance genes.
- Phenotypically resistant to multiple commonly used antibiotics; includes a documented susceptibility profile.
- Supplied as a frozen vial; recommended storage at -80°C or colder.
- Recovery: incubate at 37°C for 18-24 hours on appropriate media.
- Handle under biosafety level 2 (BSL-2) containment and follow institutional safety protocols.
Cayman Chemical FungI FuscIn 10mg
A fungal metabolite with diverse biological activities; inhibits binding of atractyloside to rat liver mitochondria in an ADP-dependent manner at 50 μM in a radioligand binding assay; reduces the glutathione content of rat liver mitochondria to 28% of controls at 20 μM; inhibits NADH oxidation in sonicated pigeon heart mitochondria preparations; competes with MIP-1α for binding to CCR5 chemokine receptors in vitro (IC50 = 21 μM)
Cayman Chemical SIvelStatsodIM salt hydra 50mg
An inhibitor of neutrophil elastase (IC50 = 44 nM for the human enzyme); selective for neutrophil elastase over trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G at 100 µM; decreases LPS-induced NF-κB nuclear translocation in isolated rat PMVECs at 50 mM; reduces pulmonary edema, increases in the number of MPO-positive cells in the lung tissue, and the severity of lung injury in a rat model of LPS-induced acute lung injury at 10 mg/kg
Cayman Chemical LTyrosInsodIum salt hydra 100g
A conditionally essential amino acid; a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones; plasma, skeletal muscle, and erythrocyte levels are decreased in patients with chronic kidney disease
ABclonal Technology Acetyl-Histone H4-K12
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes Two molecules of each of the four core histones (H2A H2B H3 and H4) form an octamer around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family Transcripts from this gene lack polyA tails but instead contain a palindromic termination element This gene is found in the large histone gene cluster on chromosome 6
California Pacific Lab & Consulting L-TYROSINE DISODIUM SALT HYDRA
NC3841286 L-TYROSINE DISODIUM SALT HYDRA
Cayman Chemical FrovatrIptnsuccInAT hydra 10mg
An agonist of 5-HT1B and 5-HT1D receptors (Kis = 2.51 and 3.98 nM, respectively); selective for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2C, 5-HT3, and 5-HT7 receptors, as well as dopamine D1, D2, and D3, histamine H1, and α1-adrenergic receptors (Kis = >50 nM); induces contractions in human basilar arteries isolated post-mortem, coronary arteries from transplant recipient hearts, and coronary arteries from donor hearts unsuitable for transplantation (EC50s = 13.8, 41.69, and 15.49 nM, respectively); increases carotid vascular resistance in closed-chest and open-chest anesthetized dogs (ED50s = 6 and 1 nmol/kg, i.v., respectively)
Cayman Chemical FrovatrIptnsuccInAT hydra 25mg
An agonist of 5-HT1B and 5-HT1D receptors (Kis = 2.51 and 3.98 nM, respectively); selective for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2C, 5-HT3, and 5-HT7 receptors, as well as dopamine D1, D2, and D3, histamine H1, and α1-adrenergic receptors (Kis = >50 nM); induces contractions in human basilar arteries isolated post-mortem, coronary arteries from transplant recipient hearts, and coronary arteries from donor hearts unsuitable for transplantation (EC50s = 13.8, 41.69, and 15.49 nM, respectively); increases carotid vascular resistance in closed-chest and open-chest anesthetized dogs (ED50s = 6 and 1 nmol/kg, i.v., respectively)
ABclonal Technology Acetyl-Histone H4-K12
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes This structure consists of approximately 146 bp of DNA wrapped around a nucleosome an octamer composed of pairs of each of the four core histones (H2A H2B H3 and H4) The chromatin fiber is further compacted through the interaction of a linker histone H1 with the DNA between the nucleosomes to form higher order chromatin structures This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family Transcripts from this gene lack polyA tails instead they contain a palindromic termination element This gene is found in a histone cluster on chromosome 1 This gene is one of four histone genes in the cluster that are duplicated this record represents the centromeric copy