Living Organisms
AdipoGen ANTS
Chemical. CAS 5398-34-5. Formula C10H7NNa2O9S3. Molecular Weight 427.34. ANTS is a highly negatively charged dye with an amino group that can be coupled to an aldehyde or ketone group to form an unstable Schiff base. The Schiff base is usually chemically reduced by sodium borohydride NaBH4 or sodium cyanoborohydride NaBCNH3 to form a stable linkage. This labeling technique has been widely used for the labeling and subsequent sequencing of oligosaccharides and glycoproteins. The negative charges of the dye facilitate the electrophoretic separation of the degradation products of carbohydrate polymers. The polyanionic dye ANTS is used together with the fluorescent cationic quencher DPX for membrane fusion studies or permeability assays. The mixture of ANTS-DPX is minimally fluorescent initially, but becomes increasingly more fluorescent upon dilution i.e. membrane fusion or leakage. ANTS also is used as a neuronal tracer.
Cayman Chemical SIvelStatsodIM salt hydra 25mg
An inhibitor of neutrophil elastase (IC50 = 44 nM for the human enzyme); selective for neutrophil elastase over trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G at 100 µM; decreases LPS-induced NF-κB nuclear translocation in isolated rat PMVECs at 50 mM; reduces pulmonary edema, increases in the number of MPO-positive cells in the lung tissue, and the severity of lung injury in a rat model of LPS-induced acute lung injury at 10 mg/kg
Cayman Chemical PemetrexedodIM salt hydra 50mg
An antifolate with anticancer activity; an inhibitor of thymidylate synthase and dihydrofolate reductase (Kis = 109 and 7 nM, respectively); has increased potency for thymidylate kinase when polyglutaminated (Ki = 1.3 nM); an inhibitor of glycinamide ribonucleotide formyltransferase (Kis = 9,300 and 65 nM for the non-glutaminated and polyglutaminated enzyme) and aminoimidazole carboxamide ribonucleotide formyltransferase (Kis = 3,600 and 265 nM for the non-glutaminated and polyglutaminated, respectively); inhibits proliferation of CCRF-CEM cells but not 5,10-dideazatetrahydrofolate-resistant CR15 cells (IC50s = 0.254 and 200 µM, respectively); reduces tumor growth in A549, H1299, and PC-9 NSCLC mouse xenograft models but not in models using the same cell lines overexpressing thymidylate kinase
Cayman Chemical ClodronatSodIM salt hydra 50mg
A non-nitrogenous bisphosphonate that inhibits hydroxyapatite crystal growth (IC50 = 1.34 µM) and bone resorption; is cytotoxic to both osteoclasts and macrophages and has been used in biological research to selectively induce apoptosis of macrophage-like cells and cancer cells
Cayman Chemical Harmalol hydrochloride hydra
A β-carboline alkaloid and an active metabolite of harmaline; an inhibitor of DYRK1A (IC50 = 0.63 µM); an inhibitor of MAO-A (IC50 = 0.66 µM); selective for DYRK1A over Cdk1, Cdk5, CK1α1, Clk4, DYRK2, Pim-1, and GSK3β but also inhibits DYRK1B and Clk1 at 10 µM; inhibits proliferation of H4 human glioblastoma cells (IC50s = 23.7 µM); reduces TCDD-induced increases in CYP1A1 levels in HepG2 cells and prevents TCDD-induced activation of AhR in guinea pig hepatic cytosolic extracts; reduces glutamate-induced cytotoxicity, cytochrome c release, caspase-3 activation, and ROS production in PC12 cells at 25 µM
Uline Teknor Apex Neverkink Xp Garden Hose - Industrial Plus, 50', 3/4” Diameter
Teknor Apex NeverkinkXp Garden Hose-Industrial Plus 50FT 3/4 Diameter
Cayman Chemical A943931hydroCLOrID hydra 25mg
A histamine H4 receptor antagonist (Ki = 3.8 nM); inhibits clobenpropit-induced scratching in mice (ED50 = 26 µmoles/kg, i.p.)
Cayman Chemical SIvelestatsodIM salt hydra 5mg
An inhibitor of neutrophil elastase (IC50 = 44 nM for the human enzyme); selective for neutrophil elastase over trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G at 100 µM; decreases LPS-induced NF-κB nuclear translocation in isolated rat PMVECs at 50 mM; reduces pulmonary edema, increases in the number of MPO-positive cells in the lung tissue, and the severity of lung injury in a rat model of LPS-induced acute lung injury at 10 mg/kg
Cayman Chemical BIX01294hydroCLOrID hydra 10mg
A selective inhibitor of G9a histone methyltransferase (IC50 = 1.7 μM); less effectively inhibits G9a-like protein (GLP; IC50 = 38 μM) and has no effect on other known histone methyltransferases
Enterprise Technology Solutions Maxell B-13 Bass Earbuds with
B-13 Bass Earbuds with Microphone 52 Cord Black
Cayman Chemical CefsulodInsodIM salt hydra
A cephalosporin antibiotic; active against 45 isolates of P. aeruginosa (MIC90 = 3.1 UG/ml) and acts synergistically against P. aeruginosa isolates when combined with gentamicin, tobramycin, amikacin, or mezlocillin; binds to P. aeruginosa PBP1a, PBP1b, and PBP3 but not PBP2, PBP4, or PBP5; increases survival in mice infected with various P. aeruginosa strains (ED50s = 1.93-137 mg/kg for all)
Cayman Chemical Cefepime hydrochloride hydra
A cephalosporin antibiotic; inhibits the growth of some clinical isolates of Corynebacterium, Streptococcus, and Staphylococcus (MIC90s = 0.03-8 μg/ml); inhibits the growth of some Citrobacter, Enterobacter, Klebsiella, Salmonella, Serratia, Shigella, and enteric bacilli species in addition to P. mirabilis and E. coli clinical isolates (MIC90s = ≤0.12-2 μg/ml); inhibits the growth of pneumococci strains (MICs = 0.5-2 mg/l) in vitro and in vivo in a mouse model of peritonitis (ED50s = 0.6-1.14 mg/kg)
Cayman Chemical CefepImehydrochlorIde hydra 1g
A cephalosporin antibiotic; inhibits the growth of some clinical isolates of Corynebacterium, Streptococcus, and Staphylococcus (MIC90s = 0.03-8 μg/ml); inhibits the growth of some Citrobacter, Enterobacter, Klebsiella, Salmonella, Serratia, Shigella, and enteric bacilli species in addition to P. mirabilis and E. coli clinical isolates (MIC90s = ≤0.12-2 μg/ml); inhibits the growth of pneumococci strains (MICs = 0.5-2 mg/l) in vitro and in vivo in a mouse model of peritonitis (ED50s = 0.6-1.14 mg/kg)
Cayman Chemical CefsulodInsodIM salt hydra
A cephalosporin antibiotic; active against 45 isolates of P. aeruginosa (MIC90 = 3.1 UG/ml) and acts synergistically against P. aeruginosa isolates when combined with gentamicin, tobramycin, amikacin, or mezlocillin; binds to P. aeruginosa PBP1a, PBP1b, and PBP3 but not PBP2, PBP4, or PBP5; increases survival in mice infected with various P. aeruginosa strains (ED50s = 1.93-137 mg/kg for all)