Isotopically Labeled Compounds
Medchemexpress LLC Formamide-d3 | 43380-64-9 | MFCD00144375 | 99.7% | 48.06 g/mol | CD3NO | 50mg
Formamide-d3 is the deuterium labeled Formamide (HY-Y0842) Formamide is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions Formamide can also be used as a decalcifying agent for rat cardiac cells Additionally formamide is widely used as a solvent or chemical raw material for ion compounds resins and plasticizers [1][2][3][4][5][6][7]
Medchemexpress LLC Quinoline-d7 | 34071-94-8 | MFCD00145200 | 98.3% | 136.2 g/mol | C9D7N | 50mg
Quinoline-d7 is the deuterium labeled Quinoline[1]
Medchemexpress LLC Hydroxylamine-d3 hydrochloride | 15588-23-5 | MFCD00075189 | 99.0% | 72.51 | ClHD3NO | 100mg
Hydroxylamine-d3 (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms such as ammonium oxidizing bacteria (AOB) ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox) Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity[1][2][3]
Medchemexpress LLC Macitentan-d4 | 1258428-05-5 | 98.0% | C19H16D4Br2N6O4S | 10MG
Macitentan-d4 is a deuterium-labeled analog of macitentan intended for use as an isotope-labeled internal standard in analytical and research workflows, especially mass spectrometry-based quantitation for pharmacokinetic and metabolite studies. The deuterated tracer provides a predictable mass shift while closely matching the physicochemical behavior of the parent compound.
- Deuterium-labeled internal standard for MS analyses.
- High purity (98.0%) suitable for quantitative work.
- Appropriate for pharmacokinetic, metabolite, and bioanalytical assays.
- Available in small milligram pack sizes for analytical use.
- Chemical formula: C19H16D4Br2N6O4S.
Medchemexpress LLC Methyl salicylate-d4 | 1219802-12-6 | 156.17 g/mol | C8H4D4O3 | 10mg
Methyl Salicylate-d4 is the deuterium labeled Methyl Salicylate[1] Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent Also used as a pesticide a denaturant a fragrance ingredient and a flavoring agent in food and tobacco products[2] A systemic acquired resistance (SAR) signal in tobacco[3] A topical nonsteroidal anti-inflammatory agent (NSAID) Methyl salicylate lactoside is a COX inhibitor[5]
Medchemexpress LLC Spermidine-d6 trihydrochloride | 98.0% | 260.67 g/mol | C7H16D6Cl3N3 | 5mg
Spermidine-d6 trihydrochloride is the deuterium labeled Spermidine-d6 (trihydrochloride) (HY-W709575)[1]
Medchemexpress LLC 2-butenedioic-2,3-d2 acid | 24461-33-4 | MFCD00144720 | 98.0% | 118.08 | C4H2D2O4 | 10mg
Maleic Acid-d2 is the deuterium labeled Maleic Acid[1] Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E coli and L monocytogenes[2][3]
Medchemexpress LLC Levamisole-d5 hydrochloride ((-)-Tetramisole-d5 hydrochloride) | 1246819-64-6 | 99.99% | 245.78 | 1 MG
Levamisole-d5 hydrochloride is a deuterium-labeled form of Levamisole hydrochloride. This compound functions as an anthelmintic and immunomodulator, classified as a synthetic imidazothiazole derivative. It also exhibits antiviral effects against HSV.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Anthelmintic properties
- Immunomodulator capabilities
- Exhibits antiviral effects against HSV
Medchemexpress LLC Tridecanoic acid-d2 | 64118-44-1 | 5mg
Tridecanoic acid-d2 is the deuterium labeled Tridecanoic acid Tridecanoic acid (N-Tridecanoic acid) a 13-carbon medium-chain saturated fatty acid can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation[1]
Medchemexpress LLC Thiamphenicol-d3 | 2211914-19-9 | 99.5% | 1 MG
Thiamphenicol-d3 is a deuterium labeled form of Thiamphenicol, a broad-spectrum antimicrobial antibiotic. As a methyl-sulfonyl derivative of Chloramphenicol, it functions by binding to the 50S ribosomal subunit, which inhibits protein synthesis. This mechanism provides a bacteriostatic effect against a range of bacteria, including Gram-negative, Gram-positive aerobic, and anaerobic types.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Metronidazole-d4 | 1261392-47-5 | 98.3% | 1 MG
Metronidazole-d4 is a deuterium-labeled Metronidazole, a nitroimidazole antibiotic medication used for anaerobic bacteria and protozoa. It is for research use only and not sold to patients. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Amitriptyline-d6 hydrochloride | 203645-63-0 | 99.9% | 1 MG
Amitriptyline-d6 hydrochloride is the deuterium-labeled version of Amitriptyline hydrochloride, an orally active tricyclic antidepressant (TCA). It primarily works by blocking SERT (Ki = 3.45 nM) and NET (Ki = 13.3 nM), which increases the concentrations of 5-hydroxytryptamine (5-HT) and norepinephrine (NE) in the synaptic cleft. It also acts as an agonist at α2A and TrkA/TrkB receptors, contributing to analgesic and neurotrophic effects by inhibiting cell apoptosis.
- Increases concentrations of 5-hydroxytryptamine and norepinephrine in synaptic cleft
- Contributes to analgesic and neurotrophic effects
- Reduces inflammation, angiogenesis, and fibrosis
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-ethyl 5-methyl ester-d3 | 1219795-30-8 | 99.8% | 1 MG
Felodipine-d3 is a deuterium-labeled variant of Felodipine, a potent dihydropyridine calcium channel antagonist. It lowers blood pressure by selectively acting on vascular smooth muscle. This anti-hypertensive agent induces autophagy and can cross the blood-brain barrier. It is suitable for research use only and can be used as a tracer or an internal standard for quantitative analysis.
- Potent vasoselective calcium channel antagonist
- Lowers blood pressure by selective action on vascular smooth muscle
- Induces autophagy
- Can cross the blood-brain barrier
- Suitable for research use only
- Used as a tracer
- Used as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS
Medchemexpress LLC Sulfamethoxazole-d4 | 1020719-86-1 | 99.3% | 1 MG
Sulfamethoxazole-d4 is a deuterium-labeled sulfonamide antibiotic with broad antibacterial activity. It functions by inhibiting bacterial folate metabolism through competition with 4-Aminobenzoic acid (PABA) for dihydropteroate synthetase and dihydropteroate reductase. This compound is suitable for studies of urinary tract infections (UTIs), prostatitis, and bronchitis.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs
- Available in solid form
BIOHIPPO GAL4-TAR-Puro LV
GAL4-TAR-Puro is a transcription factor reporter lentiviral vector designed to monitor transcription factor pathways in living cells This construct delivers a RFP reporter cassette together with a Puromycin selection marker for generation of stable cell pools The vector is provided as a ready to use Lentivirus preparation pseudotyped with VSV-G for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include Identification of protein-protein interactions (PPI) and as a reporter in mammalian two-hybrid assay The system is suitable for use with Human/mouse and can support assay development high content screening and mechanism of action studies This product is intended for research use only and is not for diagnostic or therapeutic procedures
