Isotopically Labeled Compounds
Cambridge Isotope Laboratories Glycerol (D8, 99%) | 7325-17-9 | MFCD00084149 | 5g
Glycerol (D8, 99%) | Putity: 98% | MW: 100.14 | 7325-17-9 | MFCD00084149 | 5g
Cambridge Isotope Laboratories ACETONE (13C3, 99%), 1 G, 93628-01-4
ACETONE (13C3, 99%), 1 G, 93628-01-4
Cambridge Isotope Laboratories Sodium Deuteroxide (D) 30% in D2O | 14014-06-3 | MFCD00037669 | 50 g
Sodium Deuteroxide (D) 30% in D2O | Purity: 99.5% | Mol Wt: 41 | 14014-06-3 | MFCD00037669 | 50 g
Medchemexpress LLC Mexiletine-d6 hydrochloride | 1329835-60-0 | 99.9% | C11H12D6ClNO | 1 MG
Mexiletine-d6 hydrochloride is a deuterium labeled Mexiletine hydrochloride. It acts as a Class IB antiarrhythmic and a non-selective voltage-gated sodium channel blocker.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories Deuterium Oxide (d, 99.9%) Low Paramagnetic-100 G In P
Deuterium Oxide (d, 99.9%) Low Paramagnetic-100 G In P
Medchemexpress LLC D18 | 2230218-36-5 | 98.79% | C21H28N6 | 25 MG
D18 is an immune modulator and TLR7/8 dual agonist, enhancing PD-L1 expression via epigenetic regulation to increase tumor sensitivity to PD-1/PD-L1 blockade. It also serves as an ADC cytotoxin, exhibiting strong immune activation and anti-tumor activity, frequently used in cancer research, especially for colon cancer.
- Functions as a TLR7/8 dual agonist (EC50 = 24 nM for hTLR7, 10 nM for hTLR8).
- Increases tumor sensitivity to PD-1/PD-L1 blockade.
- Exhibits strong immune activation and anti-tumor activity.
- Frequently employed in cancer research, particularly for colon cancer.
- Elevates IFN-γ, TNF-α, IL-1β, IL-12 p40, and IP-10 in hPBMCs (in vitro).
- Inhibits tumor growth in BALB/c mice bearing CT26 tumors (in vivo).
- Increases immune cell penetration.
- Demonstrates good safety.
Cambridge Isotope Laboratories Bifenthrin (D6 98%) 100 ug/mL in nonane 1 2 mL
Bifenthrin (D6 98%) 100 ug/mL in nonane 1 2 mL
Medchemexpress LLC Platycodin D2 | 66663-90-9 | MFCD29904544 | 99.8% | 1387.46 g/mol | C63H102O33 | 10 MG
Platycodin D2 is a triterpenoid saponin isolated from Platycodon grandiflorum with reported anti-cancer activity. It is supplied as a high-purity research reagent with documented solubility and storage guidance for experimental use.
- Naturally derived triterpenoid saponin
- Reported anti-cancer activity in preclinical studies
- High purity (99.78%) suitable for research applications
- CAS number 66663-90-9 for unambiguous identification
- Soluble in DMSO (100 mg/mL); in vivo formulation suggestions available
- Powder stable at -20°C for long-term storage
Cayman Chemical Sphingosine1phosphated7 d18
An internal standard for the quantification of S1P by GC- and LC-MS
Cambridge Isotope Laboratories Tetrahydrofuran-D8 (D 99 5%) 5 g amp
Tetrahydrofuran-D8 (D 99 5%) 5 g amp
Medchemexpress LLC Galanthamine-d6 | 1128109-00-1 | 99.5% | C17H15D6NO3 | 5 MG
Galanthamine-d6 (Galantamine-d6) is a deuterium-labeled form of Galanthamine, a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM. This compound is valuable as a tracer and an internal standard for quantitative analysis. Deuterium substitution can influence the pharmacokinetic and metabolic profiles of drugs, making this labeled compound useful in drug development research.
- Used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potent acetylcholinesterase (AChE) inhibitor
- Influences pharmacokinetic and metabolic profiles of drugs
Cambridge Isotope Laboratories ACID CAL FOR QNMR 5MM (160UL)
ACID CALIBRANT FOR QNMR 5mM BENZOIC ACID IN DMSO-D6 (160UL FILL VOLUME)
Medchemexpress LLC Urea-d3, methyl-d3- | 56683-43-3 | 96.8% | 80.12 | C2D6N2O | 1 MG
1-Methylureal-d6 is the deuterium-labeled (d6) isotopologue of 1-methylurea supplied as a stable isotope reference standard for analytical and research applications. It is used in mass spectrometry, method validation, and tracer studies, and a manufacturer certificate reports purity by HPLC.
- Deuterium-labeled internal standard for mass spectrometry.
- Useful for quantitative analysis and method validation.
- Suitable for metabolic and tracer studies.
- High purity confirmed by HPLC (96.8%).
- Offered in mg-scale quantities for analytical use.