Isotopically Labeled Compounds
Medchemexpress LLC DL-Alanine-d3 | 53795-94-1 | 25 MG
DL-Alanine-d3 is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. It is used as a reducing and capping agent with silver nitrate aqueous solutions for nanoparticle production, and for research of transition metal chelation. DL-alanine is also a sweetener and plays a role in the glucose-alanine cycle between tissues and liver.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Mephenytoin-d5 | 1185032-66-9 | 98.7% | 223.28 | C12H9D5N2O2 | 10 MG
Mephenytoin-d5 is a deuterium-labeled analogue of mephenytoin used as a stable-isotope tracer and internal standard for analytical and metabolic studies. The d5 labeling enables mass-differentiated detection in NMR, GC-MS, and LC-MS and supports quantitative assays and metabolism research.
- Deuterated analogue (d5) of mephenytoin for isotope tracing.
- Suitable as an internal standard for NMR, GC-MS, and LC-MS quantitative assays.
- High purity (≈98.7%) for reliable analytical performance.
- Available in small research quantities such as 10 mg with recommended frozen storage for solutions.
- CAS number 1185032-66-9 for unambiguous identification.
Medchemexpress LLC Dimethylamine-d6 hydrochloride | 53170-19-7 | MFCD00064544 | 98.0% | 1g
Dimethylamine-d6 hydrochloride is a deuterium labeled Dimethylamine hydrochloride Dimethylamine hydrochloride is the immediate precursor of dimethylnitrosamine a known potent carcinogen in a wide variety of animal species[1]
Medchemexpress LLC Acenaphthylene-d8 | 93951-97-4 | 99.5% | 160.24 | 100 MG
Acenaphthylene-d8 is the deuterium labeled Acenaphthylene. Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Imidacloprid-d4 | 1015855-75-0 | 98.9% | 5 MG
Imidacloprid-d4 is the deuterium labeled version of Imidacloprid. Imidacloprid is recognized as an effective and broadly used neonicotinoid pesticide, employed for controlling pests that affect cereals, vegetables, tea, and cotton. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Application as a tracer.
- Internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC Heptadecanoic acid | 506-12-7 | MFCD00002751 | 270.45 | 25 MG
Heptadecanoic acid is an odd-chain saturated fatty acid (OCS-FA) with oral activity. It can inhibit cell proliferation and induce apoptosis. It has antitumor activity and is associated with a number of diseases, including coronary heart disease, pre-diabetes and type 2 diabetes, and multiple sclerosis.
- Inhibits proliferation and migration of PC-9 and PC-9/GR cells
- Promotes apoptosis by activating the PI3K/Akt signaling pathway
- Increases the frequency of defecation in rats
- Studied for its potential role in lipid metabolism and as a dietary supplement
Medchemexpress LLC Candesartan-d5 | 1189650-58-5 | 95.50% | 1 MG
Candesartan-d5 is the deuterium labeled Candesartan. Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM. It is for research use only and not sold to patients. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ethambutol-d10 | 1129526-24-4 | 99.0% | 1 MG
Ethambutol-d10 is a deuterium-labeled version of Ethambutol, a bacteriostatic antimycobacterial agent that inhibits arabinosyl transferases, thereby obstructing the formation of the cell wall. Intended for research use only and not sold to patients, stable heavy isotopes like deuterium are incorporated into drug molecules as tracers for quantitation during drug development and have the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC MCPA-d3 | 352431-14-2 | 98.0% | 5 MG
MCPA-d3 is the deuterium labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide that interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. It also increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds.
- Application as a tracer.
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Thioridazine-d3 hydrochloride | 1189928-36-6 | 98.25% | 5 MG
Thioridazine-d3 hydrochloride is a deuterium-labeled Thioridazine, acting as an antagonist of dopamine receptor D2 family proteins with potent antipsychotic and anti-anxiety activities. It also inhibits PI3K-Akt-mTOR signaling pathways, exhibiting an anti-angiogenic effect, and induces antiproliferative and apoptosis effects in various cancer cells, specifically targeting cancer stem cells (CSCs).
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS methods
Medchemexpress LLC D-Glucose-13C-5 | 106032-62-6 | 98.0% | 100 MG
D-Glucose-13C-5 is the 13C labeled D-Glucose, a monosaccharide and important carbohydrate in biology. It acts as a carbohydrate sweetener, a vital component of general metabolism, and a critical signaling molecule involved in cellular metabolic status and biotic and abiotic stress responses.
- Functions as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Important carbohydrate in biological processes
- Acts as a carbohydrate sweetener
- Critical component in general metabolism
- Involved in cellular metabolic status signaling
- Participates in biotic and abiotic stress responses
Cambridge Isotope Laboratories L-ASCORBIC ACID (1-13C, 99%), 0.25 G, 178101-88-7
L-ASCORBIC ACID (1-13C, 99%), 0.25 G, 178101-88-7
Medchemexpress LLC DPPC-d9 (Synonyms: 129Y83-d9) | 63-89-8 | 95.0% | 743.09 | 100 MG
DPPC-d9 is a deuterium-labeled DPPC. DPPC is a zwitterionic phosphoglyceride used for preparing liposomal monolayers. DPPC-liposome effectively serves as a delivery vehicle for inducing immune responses against GSL antigen in mice.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Glucosamine-13C (hydrochloride) | 84247-63-2 | 216.62 | 5 MG
Glucosamine-6-13C hydrochloride is a 13C labeled form of Glucosamine hydrochloride, an amino sugar that acts as a significant precursor in the biochemical synthesis of glycosylated proteins and lipids. This product is extensively utilized in research for metabolic studies and cellular pathway analysis, offering precise tracing capabilities due to its isotopic label.
- Serves as an important precursor in biosynthesis.
- Utilized in metabolic studies.
- Aids in cellular pathway analysis.
- Provides precise tracing capabilities.
Cambridge Isotope Laboratories NICOTINAMIDE (2,6,CARBONYL-13C3, 99%; RING-1-15N, 98%), 1 MG
NICOTINAMIDE (2,6,CARBONYL-13C3, 99%; RING-1-15N, 98%), 1 MG