Isotopically Labeled Compounds
Cayman Chemical DIfloxacIn-d3 1mg
An internal standard for the quantification of difloxacin by GC- or LC-MS
Medchemexpress LLC Dexpramipexole-d3 dihydrochloride | 1432230-09-5 | 287.27 | 1 MG
Dexpramipexole-d3 dihydrochloride is a deuterium-labeled version of Dexpramipexole. It is a neuroprotective agent and a weak non-ergoline dopamine agonist.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into the molecule.
- Potential to affect pharmacokinetic and metabolic profiles.
Medchemexpress LLC Pitavastatin-d4 sodium | 574705-92-3 | 99.7% | 1 MG
Pitavastatin-d4 sodium is a deuterium-labeled version of Pitavastatin sodium. Deuteration, the process of incorporating stable heavy isotopes of hydrogen (deuterium) into drug molecules, has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC DL-Tryptophan-d3 | 340257-61-6 | 99.3% | 207.24 | 25 MG
DL-Tryptophan-d3 is the deuterium labeled DL-Tryptophan, an endogenous metabolite for research use only. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Contains stable heavy isotopes of hydrogen, carbon, and other elements.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 1-Adamantan-d15-amine | 33830-10-3 | MFCD01317436 | 98.0% | 166.34 | C10H2D15N | 10 MG
Amantadine-d15 (1-Adamantanamine-d15) is the deuterium-labeled isotopologue of amantadine supplied as a solid analytical standard for use in mass spectrometry, isotope-dilution quantitation, metabolic, and pharmacokinetic studies. The product is characterized by its molecular formula and verified purity on the certificate of analysis, and is intended for use as an internal standard or tracer in quantitative workflows.
- High isotopic labeling suitable for mass spectrometry applications.
- Purity 98.0% as reported on the certificate of analysis.
- White to off-white solid for convenient storage and handling.
- Appropriate as an internal standard for LC-MS/MS and GC-MS quantitation.
- Provided in a 10 mg quantity for analytical use.
Medchemexpress LLC Candesartan-d4 | 1346604-70-3 | 98.2% | 1 MG
Candesartan-d4 (CV-11974-d4) is the deuterium labeled Candesartan, an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. It has potent and long-lasting antihypertensive effects and is used for the research of hypertension, chronic heart failure (CHF), and traumatic brain injury (TBI).
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Erythromycin-d3 | 959119-26-7 | 95.0% | 1 MG
Erythromycin-d3 is a deuterium-labeled macrolide antibiotic produced by the actinomycete Streptomyces erythreus. It exhibits broad-spectrum antimicrobial activity by binding to bacterial 50S ribosomal subunits, thereby inhibiting RNA-dependent protein synthesis. Beyond its antibiotic properties, Erythromycin also demonstrates antitumor and neuroprotective effects in various research areas.
- Can be utilized as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cayman Chemical IndapamIde-13C-d3 500ug
An internal standard for the quantification of indapamide by GC- or LC-MS
Cambridge Isotope Laboratories TESTOSTERONE (1,2-D2, 98%), 0.1 G, 204244-83-7
TESTOSTERONE (1,2-D2, 98%), 0.1 G, 204244-83-7
Medchemexpress LLC Arachidic acid-d4 (Icosanoic acid-d4) | 1219803-69-6 | 316.56 | 1 MG
Arachidic acid-d4 is the deuterium-labeled version of Arachidic acid, a long-chain saturated fatty acid also known as Eicosanoic acid. It is naturally found in plasma phospholipids, fish, cannabis, and various plant oils. This compound is valuable as a tracer or an internal standard for quantitative analysis, especially with techniques like NMR, GC-MS, or LC-MS.
- Deuterium-labeled version of arachidic acid.
- Long-chain saturated fatty acid.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis.
- Suitable for NMR, GC-MS, or LC-MS applications.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
![Revvity Health Sciences Inc Methionine, L-[<sup>35</sup>S]-, 1mCi (37MBq), Specific Activity:>1000Ci (37.0TBq)/mmol, 10mM BME](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502809820.jpg-250.jpg)
Revvity Health Sciences Inc Methionine, L-[35S]-, 1mCi (37MBq), Specific Activity:>1000Ci (37.0TBq)/mmol, 10mM BME
Methionine, L-[35S]-, 1mCi (37MBq), Specific Activity:>1000Ci (37.0TBq)/mmol, 10mM BME
Medchemexpress LLC Resolvin D4 | 1025684-60-9 | 96.8% | 376.49 | 25 UG
Resolvin D4 (RvD4) is a specialized proresolving mediator. It can be produced in bioactive levels during *S. aureus* infection and stops neutrophil infiltration in sterile peritonitis and *S. aureus* skin infection. It enhances human macrophage and dermal fibroblast phagocytosis and efferocytosis.
- Enhances macrophage efferocytosis of apoptotic neutrophils by 40-50%
- Decreases the percentage of PMN by ~31% at 4 hours in *in vivo* studies
- Modulates the severity of thrombo-inflammatory disease
- Improves thrombus resolution