Isotopically Labeled Compounds
Medchemexpress LLC Dopamine-d5 hydrochloride | 2193106-55-5 | 99.6% | 1 MG
Dopamine-d5 hydrochloride is the deuterium labeled form of Dopamine hydrochloride, a catecholamine neurotransmitter. It plays crucial roles in the brain and body by inducing endocytosis of VEGFR2 through D2 dopamine receptors, promoting angiogenesis. This compound is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes can influence pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Nordoxepin-d4 hydrochloride | 2249819-14-3 | 99.9% | 305.84 | C18H16D4ClNO | 1 MG
Nordoxepin-d4 hydrochloride is the deuterium-labeled hydrochloride salt of nordoxepin provided for research and analytical use. It is intended primarily as an isotopically labeled internal standard or tracer in bioanalytical, pharmacokinetic, and metabolic studies, and is optimized for accurate quantification in mass spectrometry workflows.
- High isotopic and chemical purity (99.9%).
- Suitable as an internal standard for LC-MS/MS and GC-MS assays.
- Useful for bioanalytical quantification and method validation.
- Deuterium labeling enables tracer and metabolic studies.
- Hydrochloride form improves handling and stability.
- For research use only; not for human or veterinary use.
Medchemexpress LLC Difloxacin-d3 | 1173147-93-7 | 98.0% | 1 MG
Difloxacin-d3 is the deuterium-labeled form of the fluoroquinolone difloxacin supplied for research use as a stable-isotope tracer and internal standard for analytical quantification and metabolic tracing.
- Deuterium-labeled (d3) tracer suitable for LC-MS and GC-MS analysis.
- High chemical purity (~98.0%), appropriate for analytical standards.
- Solid form (white to off-white) with defined handling and storage guidance.
- Small pack sizes enable economical use for calibration and method development.
Medchemexpress LLC Ropivacaine-d7 | 684647-62-9 | 99.69% | 1 MG
Ropivacaine-d7 is a deuterium labeled Ropivacaine. Ropivacaine is a potent sodium channel blocker, inhibiting impulse conduction by reversibly blocking sodium ion influx in nerve fibers. It also acts as an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell membranes. Ropivacaine is used for the research of neuropathic pain management, and is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Velnacrine-d4 hydrochloride | 1246816-08-9 | 98.6% | 1 MG
Velnacrine-d4 hydrochloride is a deuterium-labeled form of Velnacrine, intended exclusively for research purposes. This compound is not sold to patients. The incorporation of stable heavy isotopes, such as deuterium, into drug molecules serves as tracers for quantitative analysis in drug development, with deuteration potentially affecting pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by nuclear magnetic resonance (NMR), gas chromatography-mass spectrometry (GC-MS), or liquid chromatography-mass spectrometry (LC-MS)
![Revvity Health Sciences Inc Cyclopentyl-1,3-Dipropylxanthine, 8-[Dipropyl-2,3-<sup>3</sup>H(N)]-, 1mCi (37MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502811004.jpg-250.jpg)
Revvity Health Sciences Inc Cyclopentyl-1,3-Dipropylxanthine, 8-[Dipropyl-2,3-3H(N)]-, 1mCi (37MBq)
Cyclopentyl-1,3-Dipropylxanthine, 8-[Dipropyl-2,3-3H(N)]-, 1mCi (37MBq)
Medchemexpress LLC Thymidine-13C | 478511-06-7 | 243.22 | 5 MG
Thymidine-13C is the 13C labeled Thymidine. It is a specific precursor of deoxyribonucleic acid and functions as a cell synchronizing agent. Thymidine is also a DNA synthesis inhibitor capable of arresting cells at the G1/S boundary, before DNA replication.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories Glycan-O33-13C-Gal6 (galactose-13C6 99%) 500 pmol
Glycan-O33-13C-Gal6 (galactose-13C6 99%) 500 pmol
Medchemexpress LLC Fmoc-leucine-d10 | 1190594-22-9 | MFCD06658583 | 99.4% | 363.47 | C21H13D10NO4 | 10 MG
Fmoc-leucine-d10 is a deuterium-labeled, Fmoc-protected L-leucine supplied for use as an isotopically labeled building block in peptide synthesis and as an analytical standard. The material is provided in small laboratory quantities with supporting quality and safety documents available.
Medchemexpress LLC Tinidazole-d5 | 1216767-04-2 | 1 MG
Tinidazole-d5 is the deuterium labeled form of Tinidazole, an orally available antibacterial agent. It is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa. Deuterium substitution in drug molecules can affect their pharmacokinetic and metabolic profiles, and stable heavy isotopes are incorporated as tracers for quantitation during drug development.
- Deuterium labeled compound
- Orally available antibacterial agent
- Selective activity against anaerobic bacteria and protozoa
- Can be used as a tracer and internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Metronidazole-d3 | 83413-09-6 | 99.97% | 5 MG
Metronidazole-d3 is deuterium labeled metronidazole, intended for research use only. This compound serves as a tracer and an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes, like deuterium, are incorporated into drug molecules for quantitation during drug development and can affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Moclobemide-d4 | 71320-77-9 | 99.0% | 100 UG
Moclobemide-d4 is a deuterium-labeled form of Moclobemide, a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor. It has shown to up-regulate proliferation of hippocampal progenitor cells in chronically stressed mice and is used as a tracer or internal standard in quantitative analysis. Stable heavy isotopes, like deuterium, are incorporated into drug molecules for quantitation during drug development and can influence pharmacokinetic and metabolic profiles.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Affects pharmacokinetic and metabolic profiles of drugs
- Up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice
Medchemexpress LLC Nortriptyline hydrochloride | 894-71-3 | 99.98% | 1 ML
Nortriptyline hydrochloride (Desmethylamitriptyline) is the main active metabolite of Amitriptyline, functioning as a tricyclic antidepressant. It also acts as a potent autophagy inhibitor and demonstrates anticancer effects.
- Potent autophagy inhibitor
- Anticancer effects
- Inhibits Norepinephrine transporter (NET, SLC6A2)
- Blocks Norepinephrine reuptake more potently than Serotonin
- Reduces viability and induces apoptosis in bladder cancer cells
- Inhibits bladder tumor growth in vivo
Medchemexpress LLC Maprotiline-d5 hydrochloride | 1794942-12-3 | 1 MG
Maprotiline-d5 hydrochloride is a deuterium-labeled version of Maprotiline hydrochloride, functioning as a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant. This compound is suitable for various quantitative analyses due to its stable heavy isotopes.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes for drug development tracing
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 1-hexanol-d5 | 64118-18-9 | >98.0% | 107.21 g/mol | C6H9D5O | 5 MG
1-Hexanol-d5 is the deuterium-labeled analogue of 1-hexanol supplied as a liquid stable isotope reagent for analytical and tracer applications. It is commonly used as an internal standard in mass spectrometry, quantitative analyses, and metabolic tracing where deuterium labeling improves selectivity and detection.
- Deuterium-labeled internal standard for mass spectrometry.
- High isotopic enrichment for reliable tracer and quantitation.
- Liquid physical form suitable for solution preparation.
- Stable under recommended storage conditions for long-term use.
- Available in small, pre-weighed pack sizes for analytical workflows.