Microplate Readers and Reader Accessories

Microplate readers are a type of spectrophotometer designed specifically for analyzing multiple samples in multi-well plates.

The readers detect light signals that result from biological, chemical, biochemical, or physical reactions. The signals are produced by, converted by, or transmitted through the samples and are measured by a detector. The detectors are usually photomultiplier tubes (PMT), which convert the released photons into electricity. The current is quantified by the reader’s software to produce the numerical result.

In some cases, samples are first excited by exposure to light of specific wavelengths. Filters or monochromators are used to select or restrict the wavelengths needed for emission or detection.

Single-mode microplate readers commonly measure absorbance, fluorescence, or luminescence. Multi-mode plate readers may measure absorbance, fluorescence, and luminescence with options for fluorescence polarization (FP). They may also include lasers for time-resolved fluorescence (TRF), TR-FRET, Amplified Luminescent Proximity Homogeneous Assays (ALPHA), and cell imaging.

Features may include:

Monochromator- or filter-based wavelength selection
Visible only or UV/Vis spectrum, fluorescence, and luminescence
Multiple photomultiplier tubes (PMTs) for simultaneous assays
Temperature and CO₂/O₂controls
Modular design for adding functionality

Microplate readers are used for high-throughput screening (HTS), biomarker assays, nucleic acid and protein quantification, kinetics, ELISA assays, homogeneous time resolved fluorescence (HTRF) for measuring cytokines, bioluminescence resonance energy transfer (BRET), and other techniques.

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Beckman Coulter Kit Integration Synergy H

Kit Integration Synergy H

Pricing & Availability

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Research Products International Corp 0.5 ml Tube Adapter System for use with Micro-Tube Vortexer

Optional part for use with Micro-Tube Vortexer.

Pricing & Availability

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Molecular Devices Filter Lens, 492 nm Bandpass, Microplate Reader Compatible

The Molecular Devices 492 nm filter lens (MPN 6500-0048) is a replacement optical element that isolates the 492 nm detection band for multimode microplate readers. It is intended for assays requiring targeted excitation or detection at this wavelength and for use as a service spare for compatible readers.

Provides narrowband filtration centered at 492 nm for targeted detection.
Supports absorbance and fluorescence assay modalities.
Serves as a replacement optical element for compatible multimode microplate readers.
Facilitates reliable wavelength selection for plate-based measurements.
Intended for use as an OEM spare component in instrument service and maintenance.