COVID Testing Kits
Cayman Chemical SARS-CoV-2 nutralIzng ntIb 1ea
An ALK4 and ALK5 inhibitor (IC50s 113 and 343 nM respectively) selective for ALK4 and ALK5 over a panel of 467 kinases at 1 UM inhibits ALK4 or ALK5 signaling in a reporter assay using HEK293 cells expressing ALK4 or ALK5 (IC50s 526 and 245 nM respectively) inhibits TGF-B1-induced increases in the levels of phosphorylated Smad2 in C2C12 myoblasts at 1 or 10 UM induces valvular interstitial cell proliferation neutrophil infiltration hemorrhage and fibrin deposition in rat heart valves at 150 or 500 mg/kg per day
Cayman Chemical SARS-CoV-2 nutralIzng ntIb 1UG
A PI4KIIIa inhibitor (IC50 5.01 nM) selective for PI4KIIIa over PI4KB PI3Ka PI3KB PI3K and PI4KY (IC50s 1000 2512 7943 2512 and 2512 nM respectively) inhibits replication of HCV genotypes 1a 1b and 2a in a cell-based replicon assay (IC50s 12.6 2.51 and 12.6 nM respectively)
Cayman Chemical SARSCoV2 B 1 1 7 SpIke Reag
An imidazoline receptor agonist selectively binds to imidazoline I1 and -I2 receptors over a2-ARs (IC50s 0.034 0.026 and 15 UM respectively) reduces complete Freund’s adjuvant-induced thermal and mechanical hyperalgesia in rats at 10 or 17.8 mg/kg decreases the latency to seizure onset and increases the percentage of animals with grade V seizures to a greater extent in female than male mice reverses cognitive deficits in the 5XFAD transgenic mouse model of Alzheimer’s disease at 5 mg/kg
Cayman Chemical SARS-CoV-2 Main Protease Enzy
An inducer of calcium influx enhances EV release from mBMDCs at 10 UM increases surface levels of CD86 and CD80 on mBMDCs at 10 UM an effect that can be blocked by BTP2 and increases CD86 and CD80 levels on mBMDC-derived EVs
Cayman Chemical SARSCoV2 SpIke Reagent 100dtn
An STK17B inhibitor (IC50 43 nM) selective for STK17B over STK17A (IC50 4700 nM) as well as eight additional kinases (IC50s 5200->10000 nM)
Cayman Chemical SARS-CoV-2 Main Protease Inhi
An inducer of calcium influx enhances EV release from mBMDCs at 10 UM increases surface levels of CD86 and CD80 on mBMDCs at 10 UM an effect that can be blocked by BTP2 and increases CD86 and CD80 levels on mBMDC-derived EVs
Cayman Chemical SARS-CoV-2 nsp7recombInt 100ug
A clickable RNA pseudoknot binder has been used in the synthesis of PINAD molecules for the degradation of SARS-CoV-2 RNA
Cayman Chemical SARS-CoV-2 nsp7recombInt 500ug
A clickable RNA pseudoknot binder has been used in the synthesis of PINAD molecules for the degradation of SARS-CoV-2 RNA
Cayman Chemical SARSCoV2 SpIke GlycoproteIn
A BD2 bromodomain inhibitor inhibits BD2 in BRD2 BRD3 BRD4 and BRDT (IC50s 264 98 49 and 214 nM respectively) and is selective for BD2 over BD1 (IC50s 10.96 36.31 70.55 and 50.11 UM for BRD2 BRD3 BRD4 and BDT respectively) in a TR-FRET assay inhibits IFN-Y-induced protein expression of MHC class I in K562 cells at 1 UM reduces the production of anti-KLH IgM antibodies in mice immunized with KLH at 40 mg/kg
Cayman Chemical SARSCoV2 SpIke GlycoproteIn
A BD2 bromodomain inhibitor inhibits BD2 in BRD2 BRD3 BRD4 and BRDT (IC50s 264 98 49 and 214 nM respectively) and is selective for BD2 over BD1 (IC50s 10.96 36.31 70.55 and 50.11 UM for BRD2 BRD3 BRD4 and BDT respectively) in a TR-FRET assay inhibits IFN-Y-induced protein expression of MHC class I in K562 cells at 1 UM reduces the production of anti-KLH IgM antibodies in mice immunized with KLH at 40 mg/kg
Cayman Chemical SARSCoV2 SpIk Glycoprotin 50uL
An orally bioavailable ACE and NEP inhibitor (IC50s 1.7 and 5.3 nM respectively for the human enzymes) inhibits the angiotensin I-induced pressor response in normotensive rats (ED50 0.07 Umol/kg) lowers MAP in sodium-depleted spontaneously hypertensive rats at 30 Umol/kg lowers MAP in rats when co-administered with bradykinin increases tracheal plasma extravasation in a rat model of upper airway angioedema in a dose-dependent manner
Cayman Chemical SARS-CoV-2humn nutralIzI 100ug
A synthetic peptide corresponding to an integrin cell adhesion sequence a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo
Revvity Health Sciences Inc AlphaLISA SARS-CoV2 S1 / ACE2 Binding Kit, 500 Assay Points
AlphaLISA SARS-CoV2 S1 / ACE2 Binding Kit, 500 Assay Points
Biolegend Spark NIR™ 685 anti-mouse Ki-67 [16A8]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: ICFC; Size: 100 μg
Spark NIR™ 685 anti-mouse Ki-67 [16A8]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: ICFC; Size: 100 μg