COVID Testing Kits
Cayman Chemical SARSCoV2 SpIke GlycoproteIn
A cGAS inhibitor (IC50 0.11 UM) inhibits dsDNA-induced IFN-B1-dependent gene expression in a reporter assay reduces basal Ifnb1 mRNA expression in BMDMs generated from the Trex1-/- mouse model of Aicardi-Goutières syndrome
Cayman Chemical SARSCoV2 SpIke GlycoproteIn
A BD2 bromodomain inhibitor inhibits BD2 in BRD2 BRD3 BRD4 and BRDT (IC50s 264 98 49 and 214 nM respectively) and is selective for BD2 over BD1 (IC50s 10.96 36.31 70.55 and 50.11 UM for BRD2 BRD3 BRD4 and BDT respectively) in a TR-FRET assay inhibits IFN-Y-induced protein expression of MHC class I in K562 cells at 1 UM reduces the production of anti-KLH IgM antibodies in mice immunized with KLH at 40 mg/kg
Cayman Chemical SARSCoV2 SpIke GlycoproteIn
Source: Active recombinant C-terminal rabbit IgG1 Fc-tagged SARS-CoV-2 surface glycoprotein receptor binding domain N501Y variant expressed in HEK293 cells • Amino acids: 21-243, 319-541 of P0DTC2 • MW: 50.37 kDa