Flow Cytometry Analyzer Supplies
BD Cell Analysis 3P BD™ FC Beads BV421, Flow Cytometry Compensation, Instrument Standardization, 15 pcs
BD FC Beads BV421 are specialized fluorescent beads designed for flow cytometry compensation and instrument standardization. They ensure accurate spillover values and consistent data acquisition across multiple BD flow cytometers, enhancing experimental reliability. The beads are stable at 2°C–8°C and should be stored in a foil pouch, protected from light and humidity.
BANGS LABORATORIES INC Quantum Alexa Fluor 488, 20 tests, 1 mL
Quantum Alexa Fluor 488, 20 tests, 1 mL.
AdipoGen IL-38 human rec His
Recombinant protein. Human IL-38 aa 1-152 is fused at the C-terminus to a His-tag. Source E. coli. Lyophilized. In 50mM TRIS-Cl, pH 8.0, containing 150mM NaCl. IL-38 IL-1F10 mRNA is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F family such as IL-1F5 / 6 / 8 or 9 also called IL-36Ra, IL-36alpha, IL-36beta or IL-36gamma is important to increase their biological activity. Recently it has been shown that IL-38 is N-terminally processed and secreted by apoptotic cells. Released processed IL-38 20-152 binds to the receptor Interleukin-1 receptor accessory protein-like 1 IL1RAPL1 TIGIRR-2 at the surface of macrophages. Processed IL-38-activated IL1RAPL1 reduces the production of IL-6 leading to inflammation attenuation.
AdipoGen Fc LALA-PG-KIHhGDF15 ms
Recombinant protein. The extracellular domain of mouse GDF15 aa 189-303 is fused to the C-terminus of the Fc LALA-PG Knob region of human IgG1. Fc LALA-PG KnobsGDF15 mouse and Fc LALA-PG Holes form the Fc LALA-PG-KIH humanGDF15 mouse rec. using the Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Produced using animal component-free medium. Lyophilized. Contains PBS Binds to its receptor GDNF family receptor alpha-like GFRALmouse with a ED50 < 5ng /ml. Growth and differentiation factor 15 GDF15, also known as macrophage inhibitory cytokine-1 MIC-1, is a member of the transforming growth factor TGF-beta superfamily and was initially identified in activated macrophages. GDF15 acts through a recently identified receptor called Glial-derived Neurotrophic Factor GDNF Receptor Alpha-Like GFRAL which signals through the Rearranged during Transfection RET tyrosine kinase receptor.
AdipoGen Fc LALA-PG-KIHIrisin mono
Recombinant protein. Fc LALA-PG KnobsIrisin human, aa 32-143 /mouse, aa 29-140 and Fc LALA-PG Holes form the Fc LALA-PG-KIH humanIrisin monomeric rec. using the Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin. Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Beckman Coulter Flow-Count Fluorospheres, 200 Tests, CE, IVD
Flow-Count Fluorospheres are a suspension of fluorescent microbeads used to determine absolute counts on the flow cytometer. Each fluorosphere contains a dye which has a fluorescent emission range of 525 nm to 700 nm when excited at 488 nm. They have uniform size and fluorescence intensity, and an assayed concentration allowing a direct determination of absolute counts.
Beckman Coulter TCR Zeta, Particle Size Analyzer
The Beckman Coulter TCR Zeta is a flow cytometer that uses light scattering and fluorescence to analyze the physical and chemical characteristics of cells or particles in suspension. It can measure size, granularity, and fluorescence intensity. The instrument has 3 lasers (405nm, 488nm, 633nm) and 18 fluorescence detectors to analyze up to 14 colors. It has a throughput of up to 30,000 events per second. The hydrodynamic focusing technology allows analysis of particles from 0.04 to 40 microns. The TCR Zeta streamlines multicolor panels in immunology and oncology research by providing high-content cellular analysis.
Biosure Inc BULK SHEATH SOLUTION 2X10L/CS
BioSure Bulk 8X Sheath Solution is a buffered, azide-free reagent. The product contains an antibacterial-antifungal preservative (not azide) and may not be suitable for cells that are cultured following sorting.
AdipoGen IL-38 aa20-152hmonom-KIH
Recombinant Protein. Human IL-38 aa 20-152 is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. IL-38 IL-1F10 belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F family such as IL-1F5 / 6 / 8 or 9 also called IL-36Ra, IL-36alpha, IL-36beta or IL-36gamma is important to increase their biological activity. Recently it has been shown that IL-38 is N-terminally processed and secreted by apoptotic cells.
Cayman Chemical GlypIcn3 RabbIt MoncLNal 25tSt
Immunogen: A synthetic peptide corresponding to the central region of human glypican-3 • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) Glypican-3 • Applications: FC
AdipoGen IL-38 aa1-152hmonome-KIH
Recombinant protein. Human IL-38 aa 1-152 is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. IL-38 IL-1F10 belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F family such as IL-1F5 / 6 / 8 or 9 also called IL-36Ra, IL-36alpha, IL-36beta or IL-36gamma is important to increase their biological activity. Recently it has been shown that IL-38 is N-terminally processed and secreted by apoptotic cells. Released processed IL-38 20-152 binds to the receptor Interleukin-1 receptor accessory protein-like 1 IL1RAPL1 TIGIRR-2 at the surface of macrophages.
AdipoGen VSTM5 hFc h non-lytic
Recombinant protein. The extracellular domain of human VSTM5 aa 29-147 is fused to the N-terminus of the human Fc IgG1 non-lytic mutant. Source HEK 293 cells. Lyophilized. Contains PBS. The V-set and transmembrane domain-containing protein VSTM family is composed of 8 proteins VSTM1v1, VSTM1v2, VSTM2a, VSTM2b, VSTM2L, VSTM3, VSTM4 and VSTM 5. Members of the VSTM family are associated with the regulation of functions of immune cells, adipose cells and neuronal cells. The VSTM family is an immunoglobulin Ig superfamily that shares structural similarities with the B7-like transmembrane proteins involved in immune regulation. VSTM1 and VSTM4 play positive and negative roles in macrophage activation, respectively. VSTM3 TIGIT acts as a co-inhibitory receptor that suppresses the cytokine production of T cells and NK cells.
AdipoGen IL-22 msFc ms non-lytic
Recombinant Protein. Extracellular domain of mouse IL-22 aa 34-179 is fused to the N-terminus of the mouse Fc IgG2a non-lytic mutant. Source W2. Lyophilized. Contains PBS. The IL-22 gene includes five exons and a 537 bp-long open reading frame that encodes for a 179 amino acid protein. IL-22 is a member of the IL-10 family of cytokines, which also includes IL-19, -20, -24, and -26, IL-28A/B, and IL-29 and IFNlambda. Mouse and human IL-22 share 79% homology. IL-22 is mainly produced by lymphocytes, such as T helper type 1 Th1, Th17, Th22, CD8 T cells, gammadelta T cells, natural killer cells, lymphoid tissue inducer cells, innate lymphoid type 3 ILC3 cells, and also by neutrophils. IL-22 has two heterodimeric transmembrane receptors, IL-22R1 and IL-10R2, which subsequently activate the JAK/STAT3, ERK and JNK pathways.
AdipoGen IL-2 msmonomerFc-KIH h
Recombinant Protein. Mouse IL-2 aa 21-169 is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. Interleukin-2 IL-2 is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important homeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.IL-2 promotes T cell proliferation and particularly naive T cells.
AdipoGen IL-2 hmonomericFc-KIH h
Recombinant Protein. Human IL-2 aa 21-153 is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. Interleukin-2 IL-2 is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important homeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.IL-2 promotes T cell proliferation and particularly naive T cells.