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VULM 1457 is a small-molecule research compound that potently inhibits cholesterol acyltransferase (ACAT). It reduces production and secretion of adrenomedullin and down-regulates adrenomedullin receptors in hepatoblastic cells, with reported hypolipidaemic activity and protective effects in myocardial ischaemia-reperfusion models. Provided as a high-purity research reagent (CAS 228544-65-8; MW 449.57 g/mol).
Potent ACAT inhibitor for metabolic enzyme studies.
Reduces adrenomedullin production and signaling.
Demonstrates hypolipidaemic activity in reported models.
Shows cardioprotective effects in ischaemia-reperfusion studies.
Available as a high-purity powder suitable for in vitro research.
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2'-TOM MeC(Ac) amidite is a Amidite reagent (Subcategory: 2'-OH Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. Ships on dry ice. SDS available for reference.
Specifications - CAS: 872548-65-7 - MDL: No data - InChIKey: OBHVHGNMPRNNPM-RNGKMJNNSA-N - Molecular Weight: 988.247761998 - Molecular Formula: C52H74N5O10PSi - Purity: ≥95% - Container Type: 30 mL Glass (28-400) - Pack Size: 1 g - Net Weight: 1 g - Gross Weight: 50.1 g - Commodity Code: 29349990 - Country Of Origin: China - IUPAC: (2R,3R,4R,5R)-5-(4-acetamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((triisopropylsilyl)oxy)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite - SMILES: CC(N(P(O[C@@H]1[C@H](O[C@@H](N2C=C(C(NC(C)=O)=NC2=O)C)[C@@H]1OCO[Si](C(C)C)(C(C)C)C(C)C)COC(C3=CC=C(C=C3)OC)(C4=CC=C(C=C4)OC)C5=CC=CC=C5)OCCC#N)C(C)C)C
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Rhapontigenin is a naturally occurring stilbenoid used as a research-grade bioactive compound and analytical standard; it is reported to inactivate cytochrome P450 1A1 and shows antioxidant and anticancer activities.
High purity (≥98%) suitable for research applications.
Solid powder form, soluble in common organic solvents such as DMSO.
Stable when stored under recommended conditions: powder -20°C (up to 3 years) or 4°C (up to 2 years).
Used in enzymology, cell-based assays, and as an analytical reference standard.
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Glabrol is an isoprenyl flavonoid research reagent that functions as a non-competitive inhibitor of acyl-coenzyme A: cholesterol acyltransferase (ACAT). It is intended for laboratory research use in biochemical assays and inhibitor characterization.
ABMA (N-[(5-bromo-2-methoxyphenyl)methyl]adamantan-1-amine) is a small-molecule inhibitor that protects cells against a range of intracellular toxins and pathogens. It is supplied for laboratory research as a solid and as standardized DMSO solutions, with pack sizes suitable for bench-scale experiments.
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FCPR03 is a small-molecule selective phosphodiesterase 4 (PDE4) inhibitor supplied for research use. It is a solid research compound with high reported purity and is commonly used in in vitro studies of inflammation and neurobiology.
Selective PDE4 inhibitor activity
High reported purity (≈99.8%)
Solid, white to off-white appearance
Soluble in DMSO: 100 mg/mL; ready for reconstitution as 10 mM in DMSO
Molecular weight approximately 299.31 g/mol
Available in multiple small pack sizes for research use
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Unc569 is a potent, reversible, ATP-competitive Mer receptor tyrosine kinase inhibitor used for preclinical oncology research. It exhibits low-nanomolar potency against Mer and activity against Axl and Tyro3, and is supplied as a high-purity solid or DMSO solution for biochemical and cellular studies.
High purity suitable for research use.
Potent Mer inhibition (IC50 2.9 nM).
Also inhibits Axl and Tyro3, enabling TAM-family studies.
Available as solid and DMSO solution formats for assay flexibility.
Intended for in vitro and in vivo preclinical research.
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