ABclonal Technology 488 anti-4-Hydroxynonenal
4-hydroxy-2-nonenal (4-hydroxynonenal 4-HNE) is a highly reactive aldehyde generated by the exposure of polyunsaturated fatty acids to peroxides and reactive oxygen species (ROS) It non-enzymatically forms stable protein adducts with histidine lysine and cysteine side chains that have been used as biomarkers for oxidative damage in cells Conditions where 4-HNE immunoreactivity has been observed include include inflammation neurodegenerative diseases and ischemic damage to the heart and brain