Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC Geldanamycin | 30562-34-6 | C₂₉H₄₀N₂O₉ | 1 ML
Geldanamycin is an Hsp90 inhibitor exhibiting antimicrobial activity against numerous Gram-positive and some Gram-negative bacteria. It also shows anti-influenza virus H5N1 activities. This natural product inhibitor binds to the N-terminal ATPase domain of Hsp90, inhibiting its chaperone function and inducing tumor cell death via apoptosis. It protects against neuronal injury and decreases RIP1 protein levels.
- Hsp90 inhibitor
- Exhibits antimicrobial activity
- Shows anti-influenza virus H5N1 activities
- Protects against neuronal injury
- Decreases RIP1 protein levels
- Induces tumor cell death via apoptosis
Medchemexpress LLC Chloroquine phosphate | 50-63-5 | 99.9% | 500 MG
Chloroquine phosphate is an antimalarial and anti-inflammatory agent commonly used to treat malaria and rheumatoid arthritis. It acts as an inhibitor of autophagy and toll-like receptors (TLRs). Additionally, it has shown high effectiveness in controlling SARS-CoV-2 (COVID-19) infection in vitro, with an EC50 of 1.13 μM. This product is intended for research use only and is not sold to patients.
- Antimalarial agent
- Anti-inflammatory agent
- Autophagy inhibitor
- TLR inhibitor
- SARS-CoV-2 efficacy (EC50=1.13 μM)
Medchemexpress LLC (S)-Leucic acid | 13748-90-8 | 99.2% | 132.16 | 500 MG
(S)-Leucic acid is a metabolite of Leucine. It exhibits anabolic effects, specifically promoting muscle protein synthesis. Additionally, (S)-Leucic acid can be utilized in the diagnosis of pregnancy loss.
- Metabolite of Leucine
- Promotes muscle protein synthesis
- Can be used in the diagnosis of pregnancy loss
- Appears as a solid
- Color is white to off-white
- Shipped at room temperature in continental US
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Research Products International Corp Spectinomycin Dihydrochloride Pentahydrate, 5 Grams
Spectinomycin dihydrochloride pentahydrate is an antibiotic that is commonly used in the life science marketplace. It belongs to the class of aminocyclitol antibiotics and is primarily utilized for its activity against gram-negative bacteria.
Spectinomycin dihydrochloride pentahydrate finds applications in various fields such as research, molecular biology, and biotechnology. It is commonly used as a selective agent in cell culture systems and is added to growth media to prevent the growth of bacteria that may contaminate cell lines.
Also, it is particularly effective against certain strains of gram-negative bacteria, including Escherichia coli. It works by inhibiting protein synthesis in bacteria, which ultimately leads to their death. Its selective action makes it valuable for maintaining sterile conditions and selecting cells that have taken up foreign genetic material in molecular biology experiments.
Research Products International Corp Neomycin Sulfate, 25 Grams
Neomycin Sulfate is an antibiotic that is derived from the bacterium Streptomyces fradiae and belongs to the aminoglycoside class of antibiotics. It exhibits broad-spectrum activity against Gram-negative and some Gram-positive bacteria.
In molecular biology, Neomycin Sulfate is commonly used as a selective agent in genetic engineering experiments and cell culture applications. It is often included in growth media or buffers to prevent the growth of bacteria and ensure the purity of cell lines.
Neomycin Sulfate functions by inhibiting protein synthesis in bacteria, leading to cell death. Neomycin Sulfate is also employed in microbiology research.
WARNING! This product can expose you to Neomycin sulfate, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
Frontier Specialty Chemicals 25g Tetracycline hydrochloride, 64-75-5 MFCD00078142
This item has a minimum qty of 2 per supplier requirements.
Tetracycline hydrochloride CAS: 64-75-5 MFCD00078142 Other
eMolecules BI-847325 | 1207293-36-4 | MFCD28978743 | 0.25g
AstaTech | BI-847325 | 0.25g | 411869855 | 43713 | 95.000 | 1207293-36-4 | MFCD28978743 | 464.569 | C29H28N4O2
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Apexbio Technology LLC Geldanamycin 30562-34-6 50mg
Geldanamycin is an antibiotic from Streptomyces hygroscopicus that inhibits heat shock protein 90 (Hsp90) by binding to its ATP-binding pocket This disruption affects protein folding and stabilization impacting cell proliferation stress response and tumor biology Geldanamycin is used as a molecular tool in these studies and has activity against various microbes including bacteria fungi protozoa and nematodes IC50 values range from nanomolar to micromolar levels depending on the cell line and conditions It is also applied in research on vascular relaxation glucocorticoid receptor modulation and inflammation-related signaling pathways
Selleck Chemical LLC Rapamycin (Sirolimus) 100mg 53123-88-9 AY 22989NSC-2260804
Rapamycin (Sirolimus, AY 22989, NSC-2260804) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC HY-B0278 100mg Medchemexpress, Bacitracin (Zinc) CAS:1405-89-6 Purity:>98%
Medchemexpress, HY-B0278 100mg Bacitracin (Zinc) CAS:1405-89-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15067 25mg Medchemexpress, DNQX CAS:2379-57-9 Purity:>98%
Medchemexpress, HY-15067 25mg DNQX CAS:2379-57-9 DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Gold Biotechnology Inc Ampicillin (Sodium), USP Grade 5 g
Ampicillin sodium is a member of the extended-spectrum β-lactam family and similar in structure to penicillin. It is used in the selection of antibiotic cell hybrids and has a high rate of action against many gram-negative bacterial strains. Ampicillin sodium targets non-ESBL (Extended Spectrum β-lactamase) bacteria including Staphylococcus and Streptococcus species and medically important enteric pathogens such as Shigella and Salmonella. It has been found to be effective against certain β-lactam sensitive VRE or vancomycin resistant Enterococcus species. Resistance to ampicillin is routinely utilized as a selectable marker to confirm successful cell transformation. Ampicillin Sodium is freely soluble in water.
eMolecules Medchem Express / IDE1 / 1mg / 446255707 / HY-100533 / / 1160927-48-9 / MFCD17480459 / 306.318 / C15H18N2O5
Medchem Express / IDE1 / 1mg / 446255707 / HY-100533 / / 1160927-48-9 / MFCD17480459 / 306.318 / C15H18N2O5
Research Products International Corp Doxycycline Hydrochloride, 5 Grams
Doxycycline HCl is a widely used antibiotic in the life science marketplace.
It belongs to the tetracycline class of antibiotics and exhibits broad-spectrum activity against both gram-positive and gram-negative bacteria, as well as certain other microorganisms.
In the life science marketplace, Doxycycline HCl finds applications in various fields, including research and biotechnology. It is commonly used as an antibacterial agent in cell culture systems, where it helps prevent bacterial contamination in cell lines and maintain sterile conditions.
Doxycycline HCl is also utilized in molecular biology techniques such as gene expression studies and protein production. It can be added to media to select for cells containing specific genes or recombinant DNA constructs, as it inhibits protein synthesis in bacteria and other organisms.
Medchemexpress LLC Ibuprofen-d3 | 121662-14-4 | 99.94% | C13H15D3O2 | 5 MG
Ibuprofen-d3 is a deuterium labeled Ibuprofen and functions as a COX-1 and COX-2 inhibitor. It is utilized as a tracer and internal standard for quantitative analysis in various analytical methods.
- Functions as a COX-1 and COX-2 inhibitor
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis
- Suitable for methods like NMR, GC-MS, or LC-MS
- Deuterium labeling can affect pharmacokinetic and metabolic profiles of drugs