Cell Culture Media, Supplements, and Reagents
NEOGEN Agar, Bacteriological No. 2, 10 kg
Agar, Bacteriological No. 2 is a solidifying agent for use in preparing microbiological culture media in a laboratory setting. Agar, Bacteriological No. 2 is not intended for use in the diagnosis of disease or other conditions in humans.Agar is a phycocolloid extracted from a group of red-purple algae, usually Gelidium spp. Agar was first suggested for microbiological purposes in 1881 by Fannie Hesse. By the early 1900’s, agar became the gelling agent of choice over gelatin because agar remains firm at growth temperature for many pathogens and agar is generally resistant to a breakdown by bacterial enzymes. The use of agar in microbiological media significantly contributed to the advance of microbiology, paving the way to study pure cultures.For more information visit https://www.neogen.com/solutions/Microbiology/agar-bacteriological-number-2
NEOGEN Acid Hydrolysed Casein, 10 kg
Acid Hydrolysed Casein is for use in preparing microbiological culture media in a laboratory setting, and is not intended for use in the diagnosis of disease or other conditions in humans.A soluble protein hydrolysate obtained by digesting casein with hot acid. It is almost free from growth factors, vitamins and antagonists, and these qualities make it suitable for use as a protein source in media for antibiotic and vitamin assays.For more information visit https://www.neogen.com/solutions/Microbiology/acid-hydrolysed-casein
NEOGEN Bile Salts No. 3, 5 kg
Bile Salts No. 3 is a mixture of bile salts for use in preparing microbiological culture media in a laboratory setting. Several media containing Bile Salts No. 3 are recommended in standard methods for multiple applications. Bile Salts No. 3 is not intended for use in the diagnosis of disease or other conditions in humans.Bile Salts No. 3 is a refined bile salts mixture, comprising mainly sodium cholate and sodium desoxycholate. Its primary use is as a selective agent for the isolation of Gram-negative micro-organisms, inhibiting Gram-positive cocci. Bile Salts No. 3 is prepared especially for use in MacConkey Agar and Violet Red Bile Agar. This fraction of bile is highly active allowing maximum selection of organisms of enteric origin at relatively low concentrations (0.15%) and is soluble in distilled or deionized water and neutral to slightly alkaline in pH.For more information visit https://www.neogen.com/solutions/Microbiology/bile-salts-number-3
Revvity Health Sciences Inc HTRF Tag-Lite β2 Adrenergic (HEK293) Receptor Cell line
HTRF Tag-Lite β2 Adrenergic (HEK293) Receptor Cell line
Medchemexpress LLC CHMFL-PI3KD-317 | 2244992-76-3 | 98.0% | 494.03 | 50 MG
CHMFL-PI3KD-317 is a highly potent, selective, and orally active PI3Kδ inhibitor. It exhibits high selectivity over other class I, II, and III PIKK family isoforms and effectively inhibits PI3Kδ-mediated Akt T308 phosphorylation. The compound also demonstrates significant antiproliferative effects on various cancer cells and shows favorable oral bioavailability in vivo.
- Highly potent and selective PI3Kδ inhibitor.
- Exhibits over 10-1500 fold selectivity over other PIKK family isoforms.
- Inhibits PI3Kδ-mediated Akt T308 phosphorylation in Raji cells.
- Demonstrates antiproliferative effects on cancer cells.
- Shows favorable oral bioavailability and acceptable half-life in Sprague-Dawley rats.
- Inhibits the growth of MOLM-14 tumors in mice without mortality or significant weight loss.
Selleck Chemical LLC Y15-25mg
Y15 (1,2,4,5-Benzenetetraamine tetrahydrochloride, FAK inhibitor 14) is a small-molecule FAK scaffolding inhibitor that directly inhibits FAK autophosphorylation in a dose- and time-dependent manner.
Selleck Chemical LLC 1-NM-PP1-5mg
1-NM-PP1 (PP1 Analog II, 1NM-PP1, analogue 9) is a potent inhibitor of Src family kinases with IC50 of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively. 1-NM-PP1 also inhibits CDK2-as1, CAMKII-as1 and c-Abl-as2 with IC50 of 5.0 nM, 8.0 nM and 120 nM, respectively.
ATCC CCD-112CoN; Colon Fibroblast; Human (Homo sapiens)
CCD-112CoN is a cell line exhibiting fibroblast morphology that was isolated from the large intestine of a 22-week-old, female patient. This cell line was deposited by ATCC.
eMolecules 56776-32-0 | Medchem Express | Etifoxine (hydrochloride) | 5mg | 446267541 | HY-16579 | MFCD18086857 | 337.24 | C17H18Cl2N2O
Medchem Express | Etifoxine (hydrochloride) | 5mg | 446267541 | HY-16579 | 56776-32-0 | MFCD18086857 | 337.240 | C17H18Cl2N2O
Medchemexpress LLC Sabutoclax | 1228108-65-3 | C42H40N2O8 | 5 MG
Sabutoclax is a potent and effective inhibitor of the Bcl-2 Family, targeting Bcl-2, Bcl-XL, Mcl-1, and Bfl-1. It enhances the expression of pro-apoptotic proteins such as Bax, Bim, PUMA, and survivin, playing a role in inducing cell apoptosis and inhibiting cancer cell growth.
- Potent and effective Bcl-2 family inhibitor.
- Increases Bax, Bim, PUMA, and survivin expression.
- Inhibits cell growth in human prostate and lung cancer cell lines.
- Induces cell apoptosis in human diffuse large B-cell lymphoma cells.
- Upregulates pro-apoptotic proteins in chemoresistant cells.
- Reduces tumor growth in animal models.
Medchemexpress LLC Spiramycin I | 24916-50-5 | 25 MG
Spiramycin I is a macrolide antibiotic and antiparasitic. It works by binding to the 50S subunit of the ribosome, which blocks the channel for peptide chain synthesis. This mechanism leads to inhibitory activity against Gram-positive bacteria. Additionally, Spiramycin I has shown cytotoxicity in various cancer cell lines.
- Macrolide antibiotic and antiparasitic
- Binds to 50S ribosomal subunit to block peptide synthesis
- Exhibits inhibitory activity against Gram-positive bacteria
- Demonstrates cytotoxicity in cancer cells
Selleck Chemical LLC KKL-35
KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0 9 M It has broad-spectrum antibiotic activity
Selleck Chemical LLC CORM-3
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity
Apexbio Technology LLC Clindamycin 18323-44-9 100mg
Clindamycin (CAS 18323-44-9) is a small-molecule inhibitor targeting the bacterial 50S ribosomal subunit It is designed to disrupt peptide bond formation during protein synthesis thereby inhibiting bacterial proliferation Clindamycin exerts its biological activity primarily through binding to the 50S ribosomal subunit which interrupts peptide elongation and protein assembly In biochemical research Clindamycin demonstrates antimicrobial inhibition with reported IC50 values typically in the low micromolar range depending on bacterial strains and experimental conditions Based on these pharmacological properties Clindamycin holds research potential in microbiological and pharmacological studies for evaluating antimicrobial susceptibility bacterial ribosomal functions and mechanisms of antibiotic resistance
Biolegend LEGENDplex™ Mouse Growth Factor Panel (10-plex) w/ FP Reactivity: Mouse; Apps: Multiplex - Panel; Size: 100 tests
LEGENDplex™ Mouse Growth Factor Panel (10-plex) w/ FP Reactivity: Mouse; Apps: Multiplex - Panel; Size: 100 tests