Hs00009080_cn

• Gene Symbol: AGPAT2
• Assay Reference Genome Location: Chr.9:136673144 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10555
• Gene Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
• Gene Aliases: 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
• Location: Chr.9:136673143-136687459 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGPAT2	NM_001012727.1			NP_001012745.1
	NM_006412.3			NP_006403.2
	AF000237.1			AAC51649.1
	AF011374.1			AAB64299.1
	BC000026.2			AAH00026.1
	BC004529.2			AAH04529.1
	BC007269.1			AAH07269.1
	BC019292.1			AAH19292.1
	U56418.2			AAB58776.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32979	Chr.9:136666564 - 136674090 on Build GRCh38	Gain	MIR126 EGFL7 AGPAT2
dgv13005n54	Chr.9:136605258 - 136696482 on Build GRCh38	Loss	MIR126 HSPC324 EGFL7 AGPAT2 LINC01451
nsv509334	Chr.9:136514168 - 136724663 on Build GRCh38	Insertion	NALT1 MIR126 HSPC324 FAM69B EGFL7 AGPAT2 MIR4674 MIR4673 SNHG7 LINC01451 NOTCH1
nsv951203	Chr.9:136562849 - 136770848 on Build GRCh38	Deletion	MIR126 LCN8 FAM69B EGFL7 AGPAT2 MIR6722 SNHG7 SNORA17B LINC01451 HSPC324 LOC100128593 LCN15 LCN6 SNORA17A LCN10
esv3545642	Chr.9:136672575 - 136673284 on Build GRCh38	Deletion	EGFL7 AGPAT2
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	FAM69B ABCA2 DPP7 EDF1 PTGDS SEC16A FUT7 LINC01451 C8G C9orf142 SDCCAG3 MAMDC4 CLIC3 MIR4479 MIR3621 SAPCD2 DNLZ FBXW5 NALT1 MIR126 C9orf172 AGPAT2 MIR6722 LCNL1 ENTPD2 SNORA17B TRAF2 HSPC324 SNAPC4 LOC100128593 CCDC183-AS1 C9orf139 INPP5E MIR4674 UAP1L1 CCDC183 EGFL7 LCN12 TMEM141 PMPCA PRR31 LRRC26 LCN15 LCN6 LCN10 LCN8 RABL6 LOC101930307 MAN1B1 MIR4673 MAN1B1-AS1 TMEM210 SNHG7 PHPT1 NPDC1 MIR4292 NOTCH1 C9orf163 SNORA17A CARD9 GRIN1
esv2759720	Chr.9:136356377 - 136932033 on Build GRCh38	Loss	FAM69B EGFL7 EDF1 SEC16A LINC01451 TMEM141 PMPCA SDCCAG3 MAMDC4 LCN15 LCN6 MIR4479 DNLZ LCN10 NALT1 MIR126 C9orf172 LCN8 RABL6 AGPAT2 MIR6722 GPSM1 MIR4673 SNHG7 SNORA17B PHPT1 MIR4292 TRAF2 NOTCH1 HSPC324 C9orf163 SNAPC4 LOC100128593 CCDC183-AS1 INPP5E MIR4674 CCDC183 SNORA17A CARD9
nsv8579	Chr.9:136505432 - 136760256 on Build GRCh38	Gain	NALT1 MIR126 LCN8 FAM69B EGFL7 AGPAT2 MIR6722 MIR4673 SNHG7 SNORA17B LINC01451 NOTCH1 HSPC324 LOC100128593 MIR4674 LCN15 LCN6 SNORA17A LCN10
dgv955n27	Chr.9:136583078 - 136676165 on Build GRCh38	Loss	MIR126 HSPC324 EGFL7 AGPAT2 LINC01451
nsv1053781	Chr.9:136590694 - 136722927 on Build GRCh38	Gain	MIR126 HSPC324 FAM69B EGFL7 AGPAT2 LINC01451
dgv957n27	Chr.9:136619086 - 136725859 on Build GRCh38	Loss	MIR126 HSPC324 FAM69B EGFL7 AGPAT2 SNHG7
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	NDOR1 FAM69B ABCA2 CYSRT1 DPP7 EDF1 PTGDS TPRN FUT7 FAM166A LINC01451 SSNA1 C8G RNF224 C9orf142 SLC34A3 MAMDC4 CLIC3 MIR4479 MIR3621 SAPCD2 FBXW5 MIR126 C9orf172 AGPAT2 TUBB4B MIR6722 LCNL1 ENTPD2 TOR4A SNORA17B EXD3 TRAF2 HSPC324 STPG3 LOC100128593 CCDC183-AS1 TMEM203 C9orf139 UAP1L1 CCDC183 EGFL7 LCN12 TMEM141 ANAPC2 PRR31 NELFB LRRC26 LCN15 LCN6 LCN10 LCN8 RABL6 LOC101930307 NRARP MAN1B1 MAN1B1-AS1 TMEM210 SNHG7 C9orf173-AS1 PHPT1 NPDC1 MIR4292 RNF208 SNORA17A GRIN1

More Information

Additional Information:

For this assay, SNP(s) [rs138670030] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

acyltransferase

Gene Ontology Categories:

Process(es)

positive regulation of cytokine production
positive regulation of cytokine-mediated signaling pathway
phospholipid metabolic process
phosphatidic acid biosynthetic process
epidermis development
CDP-diacylglycerol biosynthetic process
triglyceride biosynthetic process
response to antidepressant

Function(s)

1-acylglycerol-3-phosphate O-acyltransferase activity