Hs00009080_cn

• Gene Symbol: AGPAT2
• Assay Reference Genome Location: Chr.9:136673144 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10555
• Gene Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
• Gene Aliases: 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
• Location: Chr.9:136673143-136687459 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGPAT2	NM_001012727.1			NP_001012745.1
	NM_006412.3			NP_006403.2
	AF000237.1			AAC51649.1
	AF011374.1			AAB64299.1
	BC000026.2			AAH00026.1
	BC004529.2			AAH04529.1
	BC007269.1			AAH07269.1
	BC019292.1			AAH19292.1
	U56418.2			AAB58776.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13005n54	Chr.9:136605258 - 136696482 on Build GRCh38	Loss	MIR126 AGPAT2 HSPC324 EGFL7 LINC01451
esv32979	Chr.9:136666564 - 136674090 on Build GRCh38	Gain	MIR126 AGPAT2 EGFL7
nsv509334	Chr.9:136514168 - 136724663 on Build GRCh38	Insertion	MIR126 MIR4673 NALT1 NOTCH1 AGPAT2 HSPC324 MIR4674 EGFL7 LINC01451 FAM69B SNHG7
nsv951203	Chr.9:136562849 - 136770848 on Build GRCh38	Deletion	AGPAT2 HSPC324 EGFL7 LCN10 SNORA17B LCN6 SNHG7 MIR126 MIR6722 SNORA17A LOC100128593 LINC01451 LCN15 LCN8 FAM69B
esv3545642	Chr.9:136672575 - 136673284 on Build GRCh38	Deletion	AGPAT2 EGFL7
esv2759720	Chr.9:136356377 - 136932033 on Build GRCh38	Loss	EDF1 NOTCH1 AGPAT2 RABL6 GPSM1 DNLZ MIR4674 EGFL7 SDCCAG3 MIR4673 NALT1 MIR6722 MIR4292 SNORA17A PHPT1 FAM69B CCDC183-AS1 MAMDC4 PMPCA HSPC324 LCN10 SNORA17B C9orf163 MIR4479 LCN6 C9orf172 SNHG7 CARD9 MIR126 CCDC183 LOC100128593 LINC01451 TRAF2 SEC16A LCN15 LCN8 SNAPC4 INPP5E TMEM141
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	DNLZ ABCA2 GRIN1 TMEM210 MIR4674 PRR31 EGFL7 C8G MIR4673 NALT1 MIR6722 SNORA17A LCN12 FAM69B UAP1L1 FBXW5 PMPCA HSPC324 SNORA17B C9orf172 C9orf139 SNHG7 MAN1B1 CARD9 CCDC183 NPDC1 C9orf142 LOC100128593 LOC101930307 TRAF2 LCN15 LCN8 SAPCD2 EDF1 NOTCH1 AGPAT2 RABL6 FUT7 SDCCAG3 PTGDS MIR4292 DPP7 ENTPD2 PHPT1 CCDC183-AS1 MAMDC4 LCN10 C9orf163 MIR4479 LCN6 LCNL1 MIR126 MIR3621 CLIC3 LRRC26 LINC01451 SEC16A SNAPC4 INPP5E TMEM141 MAN1B1-AS1
nsv8579	Chr.9:136505432 - 136760256 on Build GRCh38	Gain	NOTCH1 AGPAT2 HSPC324 MIR4674 EGFL7 LCN10 SNORA17B LCN6 SNHG7 MIR126 MIR4673 NALT1 MIR6722 SNORA17A LOC100128593 LINC01451 LCN15 LCN8 FAM69B
dgv955n27	Chr.9:136583078 - 136676165 on Build GRCh38	Loss	MIR126 AGPAT2 HSPC324 EGFL7 LINC01451
nsv1053781	Chr.9:136590694 - 136722927 on Build GRCh38	Gain	MIR126 AGPAT2 HSPC324 EGFL7 LINC01451 FAM69B
dgv13006n54	Chr.9:136619086 - 136725859 on Build GRCh38	Loss	MIR126 AGPAT2 HSPC324 EGFL7 FAM69B SNHG7
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	C9orf173-AS1 ABCA2 GRIN1 TMEM210 PRR31 EGFL7 CYSRT1 C8G NELFB MIR6722 RNF224 SNORA17A LCN12 FAM69B UAP1L1 FBXW5 HSPC324 TMEM203 SNORA17B C9orf172 RNF208 C9orf139 SNHG7 MAN1B1 CCDC183 NRARP NPDC1 C9orf142 LOC100128593 LOC101930307 TRAF2 LCN15 LCN8 FAM166A STPG3 SAPCD2 EDF1 AGPAT2 RABL6 FUT7 PTGDS MIR4292 DPP7 SLC34A3 ENTPD2 PHPT1 ANAPC2 TPRN TOR4A CCDC183-AS1 MAMDC4 SSNA1 NDOR1 LCN10 TUBB4B MIR4479 EXD3 LCN6 LCNL1 MIR126 MIR3621 CLIC3 LRRC26 LINC01451 TMEM141 MAN1B1-AS1

More Information

Additional Information:

For this assay, SNP(s) [rs138670030] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

acyltransferase

Gene Ontology Categories:

Process(es)

positive regulation of cytokine production
positive regulation of cytokine-mediated signaling pathway
phospholipid metabolic process
phosphatidic acid biosynthetic process
epidermis development
CDP-diacylglycerol biosynthetic process
triglyceride biosynthetic process
response to antidepressant

Function(s)

1-acylglycerol-3-phosphate O-acyltransferase activity