Hs00156587_cn

• Gene Symbol: ARFIP2
• Assay Reference Genome Location: Chr.11:6480331 on build GRCh38
• Cytoband: 11p15.4

Target Gene Details

• Entrez Gene ID: 23647
• Gene Name: ADP ribosylation factor interacting protein 2
• Gene Aliases: POR1
• Location: Chr.11:6474683-6481479 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARFIP2	NM_001242854.1			NP_001229783.1
	NM_001242855.1			NP_001229784.1
	NM_001242856.1			NP_001229785.1
	NM_012402.3			NP_036534.1
	XM_005252840.4			XP_005252897.1
	AK026390.1
	AK300855.1
	AK301856.1
	AK301972.1
	AK304512.1
	AK309198.1	2	246
	AK310833.1
	AK311086.1
	AK311655.1	3	219
	BC000392.2			AAH00392.1
	DB099222.1
	U52522.1			AAA97924.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv972944	Chr.11:6478192 - 6497815 on Build GRCh38	Duplication	ARFIP2 DNHD1 TIMM10B
esv3625266	Chr.11:6460034 - 6490367 on Build GRCh38	Gain	TRIM3 ARFIP2 TIMM10B

More Information

Additional Information:

For this assay, SNP(s) [rs76285816] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

vesicle coat protein

Gene Ontology Categories:

Process(es)

movement of cell or subcellular component
small GTPase mediated signal transduction
lamellipodium assembly
actin cytoskeleton organization
ruffle organization
regulation of Arp2/3 complex-mediated actin nucleation
cell-cell adhesion

Function(s)

protein binding
GTP binding
protein domain specific binding
GTP-dependent protein binding
Rac GTPase binding
phosphatidylinositol-4-phosphate binding
cadherin binding involved in cell-cell adhesion