Hs00202430_cn

• Gene Symbol: HELZ2
• Assay Reference Genome Location: Chr.20:63558090 on build GRCh38
• Cytoband: 20q13.33

Target Gene Details

• Entrez Gene ID: 85441
• Gene Name: helicase with zinc finger 2
• Gene Aliases: PDIP-1, PRIC285
• Location: Chr.20:63558086-63574239 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HELZ2	NM_001037335.2			NP_001032412.2
	NM_033405.3			NP_208384.3
	AB051556.2
	AF517673.1			AAM74197.1
	AK074171.1			BAB84997.1
	BC150283.1
	BQ707207.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv953306	Chr.20:63151949 - 63571247 on Build GRCh38	Deletion	CHRNA4 BIRC7 NKAIN4 LOC102723788 LOC100130587 MIR3196 EEF1A2 SRMS COL20A1 FLJ16779 FNDC11 MIR4326 LOC107985425 YTHDF1 ARFGAP1 LOC100130152 PPDPF KCNQ2 PTK6 HELZ2 MIR124-3
nsv586573	Chr.20:63535645 - 63560584 on Build GRCh38	Loss	SRMS PTK6 HELZ2 FNDC11
dgv521n27	Chr.20:63522433 - 63566995 on Build GRCh38	Loss	SRMS PTK6 HELZ2 FNDC11
nsv9825	Chr.20:62775470 - 63601330 on Build GRCh38	Gain	LINC00659 OGFR GID8 BIRC7 MIR3196 OGFR-AS1 FLJ16779 COL9A3 MIR4326 DIDO1 LOC63930 MRGBP ARFGAP1 LOC100130152 KCNQ2 PTK6 MIR124-3 TCFL5 CHRNA4 SLC17A9 DPH3P1 LOC107985428 NKAIN4 LOC102723788 LOC100130587 EEF1A2 SRMS COL20A1 FNDC11 LOC107985425 YTHDF1 HAR1A GMEB2 LINC01056 PPDPF HAR1B LINC00029 HELZ2 BHLHE23
nsv470563	Chr.20:63486715 - 63793308 on Build GRCh38	Loss	RTEL1-TNFRSF6B ARFRP1 LOC100505771 EEF1A2 STMN3 SRMS RTEL1 LIME1 FNDC11 SLC2A4RG ZGPAT GMEB2 ZBTB46 TNFRSF6B PPDPF PTK6 HELZ2
nsv834034	Chr.20:63462825 - 63625901 on Build GRCh38	Loss	GMEB2 EEF1A2 PPDPF SRMS KCNQ2 PTK6 HELZ2 FNDC11
dgv35n64	Chr.20:63540916 - 63581575 on Build GRCh38	Loss	SRMS HELZ2 FNDC11
esv2758806	Chr.20:63470996 - 63745014 on Build GRCh38	Gain+Loss	RTEL1-TNFRSF6B ARFRP1 LOC100505771 EEF1A2 STMN3 SRMS RTEL1 LIME1 FNDC11 SLC2A4RG ZGPAT GMEB2 ZBTB46 TNFRSF6B PPDPF KCNQ2 PTK6 HELZ2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
cellular lipid metabolic process
positive regulation of transcription from RNA polymerase II promoter

Function(s)

DNA binding
helicase activity
protein binding
ATP binding
ligand-dependent nuclear receptor transcription coactivator activity
poly(A) RNA binding
metal ion binding