Hs00212114_cn

• Gene Symbol: UBE2L6
• Assay Reference Genome Location: Chr.11:57567616 on build GRCh38
• Cytoband: 11q12.1

Target Gene Details

• Entrez Gene ID: 9246
• Gene Name: ubiquitin conjugating enzyme E2 L6
• Gene Aliases: RIG-B, UBCH8
• Location: Chr.11:57551655-57568330 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2L6	NM_004223.4			NP_004214.1
	NM_198183.2			NP_937826.1
	AF031141.1			AAB86433.1
	AF061736.1			AAD17525.1
	AK093462.1
	AK129621.1
	AK226165.1
	AK315755.1
	BC032491.1			AAH32491.1
	CR457126.1			CAG33407.1
	DA097307.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832163	Chr.11:57531881 - 57713578 on Build GRCh38	Gain	TMX2 MED19 ZDHHC5 SMTNL1 MIR130A UBE2L6 SERPING1 TMX2-CTNND1 CLP1 YPEL4

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

cellular protein modification process
protein ubiquitination
modification-dependent protein catabolic process
translesion synthesis
ISG15-protein conjugation
negative regulation of type I interferon production
cellular protein metabolic process

Function(s)

ubiquitin-protein transferase activity
protein binding
ISG15 transferase activity
ubiquitin binding