Hs00254702_cn

• Gene Symbol: TIGIT
• Assay Reference Genome Location: Chr.3:114295630 on build GRCh38
• Cytoband: 3q13.31

Target Gene Details

• Entrez Gene ID: 201633
• Gene Name: T-cell immunoreceptor with Ig and ITIM domains
• Gene Aliases: VSIG9, VSTM3, WUCAM
• Location: Chr.3:114293986-114310288 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TIGIT	NM_173799.3	2	223	NP_776160.2
	XM_011512538.1	2	211	XP_011510840.1
	AK097192.1	2	181	BAC04973.1
	AL833175.1	3	2963	CAI46183.1
	BC101288.1	2	180	AAI01289.1
	BC101289.1	2	180	AAI01290.1
	BC101290.1	2	180	AAI01291.1
	BC101291.1	2	180	AAI01292.1
	BX640915.1	1	87	CAE45956.1
	EU675310.1	2	223

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv921e214	Chr.3:114256209 - 114297720 on Build GRCh38	Gain	TIGIT

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
cell recognition
negative regulation of interleukin-12 production
positive regulation of interleukin-10 production
negative regulation of T cell activation

Function(s)

receptor activity
receptor binding
protein binding
protein homodimerization activity
cell adhesion molecule binding