Hs00265361_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1068669 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2	2	497	NP_001245257.1
	NM_001321232.1	2	433	NP_001308161.1
	NM_012292.4	2	586	NP_036424.2
	XM_006722713.1	2	586	XP_006722776.1
	XM_011527858.1	2	433	XP_011526160.1
	AK300341.1	2	489
	AK304271.1	2	457
	AK304765.1
	BC035564.1	2	331	AAH35564.1
	BC065223.1	2	578	AAH65223.1
	D86976.1	2	434
	DB148385.1	2	433
	DB162560.1
	DC382305.1	2	497

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	EFNA2 ATP5D POLR2E STK11 CIRBP C19orf24 LOC102725180 MIDN ARHGAP45 CBARP GPX4 CIRBP-AS1 ABCA7 SBNO2
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	RNU6-9 EFNA2 ATP5D RNU6-2 CNN2 POLR2E KISS1R LOC105372235 R3HDM4 STK11 GRIN3B CIRBP C19orf24 TMEM259 LOC102725180 MIDN ARHGAP45 CBARP WDR18 GPX4 CIRBP-AS1 ABCA7 SBNO2 ARID3A
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	EFNA2 ATP5D CNN2 POLR2E STK11 CIRBP C19orf24 LOC102725180 MIDN ARHGAP45 CBARP GPX4 CIRBP-AS1 ABCA7 SBNO2
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	RNU6-9 EFNA2 RNU6-2 CNN2 R3HDM4 STK11 C19orf24 MED16 LOC102725180 ARHGAP45 CBARP WDR18 SBNO2 ARID3A ATP5D POLR2E KISS1R LOC105372235 GRIN3B CIRBP TMEM259 MIDN GPX4 CIRBP-AS1 ABCA7
esv3643383	Chr.19:1012555 - 1069137 on Build GRCh38	Gain	TMEM259 RNU6-2 CNN2 ARHGAP45 ABCA7
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	POLR2E ARHGAP45 GPX4 ABCA7 SBNO2
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	TMEM259 RNU6-2 CNN2 POLR2E LOC105372235 ARHGAP45 WDR18 GPX4 ABCA7 SBNO2 ARID3A GRIN3B
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	TMEM259 RNU6-2 CNN2 POLR2E LOC105372235 ARHGAP45 WDR18 GPX4 ABCA7 SBNO2 ARID3A GRIN3B
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	RNU6-9 MIR3187 RNU6-2 CNN2 TPGS1 LOC101928450 R3HDM4 PALM POLRMT MED16 THEG CFD PRTN3 ARHGAP45 PTBP1 FGF22 WDR18 PRSS57 CDC34 HCN2 ARID3A POLR2E RNF126 KISS1R LOC105372235 ODF3L2 MIR4745 FSTL3 AZU1 ELANE MISP GRIN3B SHC2 TMEM259 PLPPR3 GZMM C2CD4C GPX4 MADCAM1 ABCA7 BSG
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	TMEM259 RNU6-2 CNN2 POLR2E ARHGAP45 GPX4 ABCA7 SBNO2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding