Hs00272031_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143991928 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1			NP_000828.1
	NM_001009184.1			NP_001009184.1
	AB097026.1			BAC77379.1
	AK127640.1
	AK294127.1
	BC041788.1			AAH41788.2
	BC084553.1			AAH84553.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PARP10 GRINA PLEC
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	MIR6893 BOP1 LRRC14 MIR661 SPATC1 PLEC MIR6848 SMPD5 PPP1R16A TONSL SHARPIN PARP10 SLC39A4 SCX EXOSC4 CPSF1 MIR1234 DGAT1 ADCK5 LOC101928902 WDR97 CYHR1 RECQL4 GPAA1 MROH1 KIFC2 VPS28 SCRT1 FOXH1 MFSD3 MIR6849 MAF1 FBXL6 CYC1 HGH1 MIR7112 MIR6847 LOC101928953 TMEM249 GRINA MIR939 HSF1 TONSL-AS1 OPLAH SLC52A2 GPT MIR6846
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	MIR6893 BOP1 LRRC14 MIR661 SPATC1 PLEC MIR6848 SMPD5 PPP1R16A TONSL SHARPIN PARP10 SLC39A4 SCX EXOSC4 CPSF1 MIR1234 DGAT1 ADCK5 LOC101928902 WDR97 CYHR1 RECQL4 GPAA1 MROH1 KIFC2 VPS28 SCRT1 FOXH1 MFSD3 MIR6849 MAF1 FBXL6 CYC1 HGH1 MIR7112 MIR6847 LOC101928953 TMEM249 GRINA MIR939 HSF1 TONSL-AS1 OPLAH SLC52A2 GPT MIR6846
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	MAF1 SPATC1 PLEC SMPD5 CYC1 SHARPIN MIR6847 PARP10 GRINA EXOSC4 WDR97 OPLAH GPAA1 MIR6846
dgv12431n54	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	EPPK1 MAF1 MIR661 SPATC1 PLEC SMPD5 CYC1 HGH1 SHARPIN MIR6847 PARP10 GRINA EXOSC4 WDR97 OPLAH GPAA1 MROH1 MIR6846
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	EPPK1 MAF1 MIR661 SPATC1 PLEC SMPD5 CYC1 SHARPIN MIR6847 PARP10 GRINA EXOSC4 WDR97 OPLAH GPAA1 MIR6846
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	SCRIB LOC642574 EPPK1 MIR661 SPATC1 PUF60 PLEC SMPD5 MIR6847 PARP10 MIR6845 GRINA EXOSC4 NRBP2 OPLAH MIR937 MIR6846
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	PARP10 GRINA EXOSC4 MIR661 SPATC1 OPLAH GPAA1 PLEC SMPD5 CYC1 MIR6847 MIR6846
dgv12433n54	Chr.8:143902404 - 144120626 on Build GRCh38	Gain	MAF1 MIR661 SPATC1 PLEC SMPD5 CYC1 SHARPIN MIR6847 PARP10 GRINA EXOSC4 WDR97 OPLAH GPAA1 MIR6846
nsv612906	Chr.8:143917935 - 144090784 on Build GRCh38	Loss	PARP10 GRINA EXOSC4 MIR661 SPATC1 OPLAH GPAA1 PLEC SMPD5 MIR6847 MIR6846

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding