Hs00272031_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143991928 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1			NP_000828.1
	NM_001009184.1			NP_001009184.1
	AB097026.1			BAC77379.1
	AK127640.1
	AK294127.1
	BC041788.1			AAH41788.2
	BC084553.1			AAH84553.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PARP10 GRINA PLEC
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	MIR7112 HGH1 TONSL-AS1 MIR6849 SMPD5 MROH1 KIFC2 CYC1 SCX MIR6847 MAF1 FOXH1 MIR6846 MIR1234 RECQL4 GPAA1 LRRC14 PLEC MIR6893 GPT TMEM249 LOC101928953 HSF1 PARP10 SLC52A2 GRINA BOP1 WDR97 SHARPIN MIR6848 VPS28 MFSD3 OPLAH PPP1R16A CPSF1 EXOSC4 MIR661 FBXL6 SPATC1 ADCK5 TONSL CYHR1 MIR939 SCRT1 LOC101928902 DGAT1 SLC39A4
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	MIR7112 HGH1 TONSL-AS1 MIR6849 SMPD5 MROH1 KIFC2 CYC1 SCX MIR6847 MAF1 FOXH1 MIR6846 MIR1234 RECQL4 GPAA1 LRRC14 PLEC MIR6893 GPT TMEM249 LOC101928953 HSF1 PARP10 SLC52A2 GRINA BOP1 WDR97 SHARPIN MIR6848 VPS28 MFSD3 OPLAH PPP1R16A CPSF1 EXOSC4 MIR661 FBXL6 SPATC1 ADCK5 TONSL CYHR1 MIR939 SCRT1 LOC101928902 DGAT1 SLC39A4
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	SMPD5 PARP10 GRINA WDR97 SHARPIN OPLAH CYC1 MIR6847 MAF1 EXOSC4 MIR6846 SPATC1 GPAA1 PLEC
dgv906n27	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	HGH1 SMPD5 PARP10 MROH1 GRINA WDR97 SHARPIN OPLAH CYC1 MIR6847 MAF1 EXOSC4 MIR661 MIR6846 SPATC1 EPPK1 GPAA1 PLEC
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	SMPD5 PARP10 GRINA WDR97 SHARPIN OPLAH CYC1 MIR6847 MAF1 EXOSC4 MIR661 MIR6846 SPATC1 EPPK1 GPAA1 PLEC
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	PUF60 SMPD5 PARP10 GRINA OPLAH NRBP2 MIR6845 LOC642574 MIR6847 EXOSC4 MIR661 MIR6846 SPATC1 SCRIB EPPK1 PLEC MIR937
dgv12432n54	Chr.8:143902404 - 144007080 on Build GRCh38	Loss	MIR661 PARP10 GRINA PLEC
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	CYC1 MIR6847 EXOSC4 MIR661 MIR6846 SPATC1 SMPD5 PARP10 GPAA1 GRINA PLEC OPLAH
nsv612907	Chr.8:143917935 - 144097007 on Build GRCh38	Gain+Loss	CYC1 MIR6847 EXOSC4 MIR661 MIR6846 SPATC1 SMPD5 PARP10 GPAA1 GRINA PLEC OPLAH

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding