Hs00299221_cn

• Gene Symbol: AKT3
• Assay Reference Genome Location: Chr.1:243489108 on build GRCh38
• Cytoband: 1q43

Target Gene Details

• Entrez Gene ID: 10000
• Gene Name: AKT serine/threonine kinase 3
• Gene Aliases: MPPH, MPPH2, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
• Location: Chr.1:243488233-243851079 on Build GRCh38
• Assay Gene Location: Within Intron 22

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AKT3	NM_181690.2			NP_859029.1
	AY005799.1			AAF91073.1
	BC121154.2

Target Gene Details

• Entrez Gene ID: 10806
• Gene Name: serologically defined colon cancer antigen 8
• Gene Aliases: BBS16, CCCAP, CCCAP SLSN7, HSPC085, NPHP10, NY-CO-8, SLSN7, hCCCAP
• Location: Chr.1:243255328-243500092 on Build GRCh38
• Assay Gene Location: Overlaps Exon 24 - Intron 24

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SDCCAG8	NM_006642.3			NP_006633.1
	XM_005273013.4			XP_005273070.1
	XM_005273018.1			XP_005273075.1
	XM_005273021.4			XP_005273078.1
	XM_005273022.3			XP_005273079.1
	XM_006711727.3			XP_006711790.1
	XM_006711728.3			XP_006711791.1
	XM_011544021.2			XP_011542323.1
	XM_011544022.2			XP_011542324.1
	XM_011544024.2			XP_011542326.1
	XM_011544026.2			XP_011542328.1
	XM_011544028.2			XP_011542330.1
	XM_011544030.2			XP_011542332.1
	XM_017000105.1			XP_016855594.1
	XM_017000106.1			XP_016855595.1
	XM_017000107.1			XP_016855596.1
	XM_017000108.1			XP_016855597.1
	AF039690.1			AAC18039.1
	AF250731.1			AAO27830.1
	AK297105.1
	AK299212.1
	AK299249.1
	BC045832.1			AAH45832.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833070	Chr.1:243339809 - 243537501 on Build GRCh38	Gain	MIR4677 AKT3 SDCCAG8
nsv1013039	Chr.1:243460621 - 243501269 on Build GRCh38	Gain	AKT3 SDCCAG8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

mitochondrial genome maintenance
protein phosphorylation
signal transduction
peptidyl-serine phosphorylation
intracellular signal transduction
G2/M transition of mitotic cell cycle
neuron migration
establishment of cell polarity
tube formation
centrosome organization

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding