Hs00341593_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1079753 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Within Exon 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2	12	1576	NP_001245257.1
	NM_001282334.1	2	1463	NP_001269263.1
	NM_001282335.1	11	1142	NP_001269264.1
	NM_001321232.1	12	1512	NP_001308161.1
	NM_012292.4	12	1665	NP_036424.2
	XM_006722713.1	12	1665	XP_006722776.1
	XM_011527858.1	12	1512	XP_011526160.1
	XM_011527860.2	3	485	XP_011526162.1
	AK122776.1	2	654
	AK128097.1	11	1142
	AK300341.1	12	1568
	AK304271.1	12	1536
	AK304765.1	11	1183
	BC035564.1	12	1410	AAH35564.1
	BC065223.1	12	1657	AAH65223.1
	BU838153.1	2	125
	D86976.1	12	1513
	DB157802.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	STK11 CIRBP-AS1 MIDN C19orf24 CIRBP ARHGAP45 GPX4 LOC102725180 ATP5D CBARP EFNA2 SBNO2 POLR2E ABCA7
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	STK11 CIRBP-AS1 MIDN RNU6-2 C19orf24 CIRBP ARHGAP45 GPX4 LOC102725180 LOC105372235 GRIN3B ATP5D CNN2 ARID3A R3HDM4 CBARP EFNA2 SBNO2 TMEM259 RNU6-9 WDR18 KISS1R POLR2E ABCA7
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	STK11 CIRBP-AS1 MIDN C19orf24 CIRBP ARHGAP45 GPX4 LOC102725180 ATP5D CNN2 CBARP EFNA2 SBNO2 POLR2E ABCA7
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	STK11 CIRBP-AS1 MIDN RNU6-2 ARHGAP45 LOC105372235 MED16 ATP5D ARID3A RNU6-9 KISS1R POLR2E ABCA7 C19orf24 CIRBP GPX4 LOC102725180 GRIN3B CNN2 R3HDM4 CBARP EFNA2 SBNO2 TMEM259 WDR18
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	SBNO2 ARHGAP45 GPX4 POLR2E ABCA7
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	GRIN3B CNN2 ARID3A RNU6-2 SBNO2 TMEM259 ARHGAP45 GPX4 WDR18 LOC105372235 POLR2E ABCA7
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	GRIN3B CNN2 ARID3A RNU6-2 SBNO2 TMEM259 ARHGAP45 GPX4 WDR18 LOC105372235 POLR2E ABCA7
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	RNU6-2 ARHGAP45 MIR3187 LOC105372235 MED16 HCN2 ARID3A THEG MISP FSTL3 ODF3L2 C2CD4C RNU6-9 KISS1R LOC101928450 POLR2E ABCA7 RNF126 MIR4745 SHC2 CFD FGF22 CDC34 ELANE GPX4 PLPPR3 POLRMT GZMM PALM MADCAM1 GRIN3B CNN2 R3HDM4 AZU1 PRTN3 TMEM259 WDR18 PRSS57 TPGS1 PTBP1 BSG
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	CNN2 RNU6-2 SBNO2 TMEM259 ARHGAP45 GPX4 POLR2E ABCA7

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding