Hs00343457_cn

• Gene Symbol: MEGF6
• Assay Reference Genome Location: Chr.1:3490196 on build GRCh38
• Cytoband: 1p36.32

Target Gene Details

• Entrez Gene ID: 1953
• Gene Name: multiple EGF like domains 6
• Gene Aliases: EGFL3
• Location: Chr.1:3487942-3624757 on Build GRCh38
• Assay Gene Location: Within Exon 41

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MEGF6	NM_001409.3	37	5185	NP_001400.3
	XM_006710406.3	34	4820	XP_006710469.1
	XM_011540885.1	38	5490	XP_011539187.1
	XM_011540886.1	37	5361	XP_011539188.1
	XM_011540887.2	33	4698	XP_011539189.1
	XM_017000533.1	37	5358	XP_016856022.1
	AB011539.2	30	4225	BAA32467.2
	AB231860.1	37	5186
	AF086226.1	1	311

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2758915	Chr.1:3372374 - 3632289 on Build GRCh38	Gain	PRDM16 TPRG1L ARHGEF16 MEGF6 WRAP73 MIR551A
nsv470687	Chr.1:3356499 - 3763210 on Build GRCh38	Loss	TP73 PRDM16 CCDC27 TPRG1L ARHGEF16 TP73-AS1 MEGF6 WRAP73 MIR551A
nsv1012423	Chr.1:3477686 - 4747449 on Build GRCh38	Gain	TP73 DFFB ARHGEF16 LINC01134 SMIM1 MIR551A CEP104 C1orf174 CCDC27 TPRG1L LOC284661 TP73-AS1 LINC01346 MEGF6 AJAP1 WRAP73 LRRC47
nsv951959	Chr.1:3051037 - 3812036 on Build GRCh38	Deletion	TP73 MIR4251 PRDM16 ARHGEF16 SMIM1 MIR551A LOC105378604 CCDC27 TPRG1L TP73-AS1 LINC00982 MEGF6 WRAP73 LRRC47
esv3893545	Chr.1:3460878 - 3512044 on Build GRCh38	Loss	ARHGEF16 MEGF6
nsv830203	Chr.1:3446374 - 3607752 on Build GRCh38	Loss	ARHGEF16 MEGF6 MIR551A
nsv299	Chr.1:3476928 - 3512705 on Build GRCh38	Insertion	ARHGEF16 MEGF6

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

extracellular matrix protein

Gene Ontology Categories:

Process(es)

biological_process

Function(s)

calcium ion binding
protein binding