Hs00350286_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137181736 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 7 - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	TMEM210 MIR3621 UAP1L1 DPP7 TMEM203 RNF224 SSNA1 CYSRT1 TPRN NDOR1 LOC101930307 LRRC26 RNF208 MAN1B1-AS1 SLC34A3 ANAPC2 GRIN1 MAN1B1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	C9orf173-AS1 TMEM203 STPG3 RNF224 SSNA1 CYSRT1 TPRN EXD3 NDOR1 NELFB RNF208 NRARP SLC34A3 FAM166A TOR4A ANAPC2 TUBB4B
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	FUT7 CCDC183 DPP7 RNF224 NPDC1 EDF1 NELFB RABL6 PTGDS C9orf142 ENTPD2 ABCA2 CLIC3 TMEM210 MIR3621 C9orf139 TRAF2 TMEM203 STPG3 SSNA1 EXD3 ENTPD8 MAMDC4 LRRC26 RNF208 PNPLA7 SLC34A3 C8G GRIN1 TUBB4B MIR7114 LCNL1 PHPT1 NOXA1 UAP1L1 NDOR1 PRR31 SAPCD2 ANAPC2 LCN12 FBXW5 NSMF C9orf173-AS1 MIR4292 MIR4479 CCDC183-AS1 CYSRT1 TPRN LOC101930307 NRARP MAN1B1-AS1 FAM166A TOR4A C9orf172 MAN1B1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TMEM210 MIR3621 C9orf173-AS1 TMEM203 STPG3 RNF224 SSNA1 CYSRT1 TPRN EXD3 NDOR1 NELFB LRRC26 RNF208 NRARP SLC34A3 FAM166A TOR4A ANAPC2 GRIN1 TUBB4B
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	NOXA1 TMEM210 MIR3621 C9orf173-AS1 TMEM203 STPG3 RNF224 SSNA1 CYSRT1 TPRN EXD3 NDOR1 ENTPD8 NELFB LRRC26 RNF208 NRARP SLC34A3 FAM166A TOR4A ANAPC2 GRIN1 TUBB4B
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	FUT7 TMEM210 MIR3621 C9orf139 UAP1L1 DPP7 NPDC1 SSNA1 LOC101930307 LRRC26 MAN1B1-AS1 SAPCD2 ANAPC2 GRIN1 MAN1B1 ENTPD2
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	MIR6722 FUT7 CCDC183 DPP7 RNF224 NPDC1 EDF1 NELFB RABL6 FAM69B PTGDS C9orf142 LCN15 ENTPD2 ABCA2 CLIC3 TMEM210 MIR3621 C9orf139 TRAF2 TMEM203 STPG3 LCN10 SSNA1 EXD3 TMEM141 MAMDC4 LRRC26 RNF208 SLC34A3 C8G EGFL7 GRIN1 SNORA17A TUBB4B LCNL1 PHPT1 LCN6 AGPAT2 LCN8 UAP1L1 NDOR1 PRR31 LINC01451 HSPC324 SAPCD2 ANAPC2 LOC100128593 SNHG7 LCN12 FBXW5 MIR126 C9orf173-AS1 MIR4292 MIR4479 CCDC183-AS1 CYSRT1 TPRN LOC101930307 NRARP MAN1B1-AS1 FAM166A TOR4A SNORA17B C9orf172 MAN1B1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity