Hs00350286_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137181736 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 7 - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	RNF208 UAP1L1 RNF224 SSNA1 TPRN ANAPC2 TMEM210 MAN1B1-AS1 GRIN1 SLC34A3 LRRC26 MIR3621 NDOR1 CYSRT1 LOC101930307 DPP7 MAN1B1 TMEM203
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	RNF208 RNF224 SSNA1 TPRN ANAPC2 EXD3 SLC34A3 NDOR1 NELFB CYSRT1 NRARP STPG3 TUBB4B C9orf173-AS1 FAM166A TMEM203 TOR4A
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	ABCA2 PHPT1 LCN12 CLIC3 CCDC183 SLC34A3 MIR7114 MIR3621 MIR4479 CYSRT1 SAPCD2 EDF1 FAM166A FBXW5 ENTPD8 LCNL1 UAP1L1 RNF224 C9orf172 EXD3 MAN1B1-AS1 GRIN1 C9orf139 MIR4292 NPDC1 STPG3 LOC101930307 C9orf173-AS1 DPP7 C8G TRAF2 PTGDS NOXA1 SSNA1 RABL6 ENTPD2 PRR31 LRRC26 PNPLA7 NELFB TUBB4B MAN1B1 TMEM203 NSMF RNF208 CCDC183-AS1 TPRN FUT7 C9orf142 ANAPC2 TMEM210 NDOR1 NRARP MAMDC4 TOR4A
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	RNF208 RNF224 SSNA1 TPRN ANAPC2 EXD3 TMEM210 GRIN1 SLC34A3 LRRC26 MIR3621 NDOR1 NELFB CYSRT1 NRARP STPG3 TUBB4B C9orf173-AS1 FAM166A TMEM203 TOR4A
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	UAP1L1 SSNA1 ENTPD2 FUT7 ANAPC2 TMEM210 MAN1B1-AS1 GRIN1 C9orf139 LRRC26 MIR3621 NPDC1 SAPCD2 LOC101930307 DPP7 MAN1B1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	RNF208 ENTPD8 RNF224 SSNA1 TPRN ANAPC2 EXD3 TMEM210 GRIN1 SLC34A3 LRRC26 MIR3621 NDOR1 NELFB CYSRT1 NRARP STPG3 TUBB4B C9orf173-AS1 FAM166A TMEM203 NOXA1 TOR4A
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	ABCA2 PHPT1 LCN8 LOC100128593 LCN10 LCN12 EGFL7 CLIC3 CCDC183 SLC34A3 MIR3621 MIR4479 MIR126 CYSRT1 TMEM141 SAPCD2 EDF1 SNORA17A LCN15 FAM166A FBXW5 LCNL1 UAP1L1 RNF224 C9orf172 AGPAT2 EXD3 MAN1B1-AS1 GRIN1 C9orf139 MIR4292 NPDC1 STPG3 LOC101930307 MIR6722 C9orf173-AS1 DPP7 SNHG7 C8G TRAF2 PTGDS FAM69B SSNA1 RABL6 ENTPD2 SNORA17B PRR31 LRRC26 NELFB TUBB4B MAN1B1 TMEM203 RNF208 CCDC183-AS1 TPRN FUT7 C9orf142 ANAPC2 TMEM210 LINC01451 LCN6 NDOR1 NRARP HSPC324 MAMDC4 TOR4A

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity