Hs00362940_cn

• Gene Symbol: GUSBP11
• Assay Reference Genome Location: Chr.22:23691372 on build GRCh38
• Cytoband: 22q11.23

Target Gene Details

• Entrez Gene ID: 91316
• Gene Name: glucuronidase, beta pseudogene 11
• Gene Aliases: -
• Location: Chr.22:23638487-23717423 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GUSBP11	NR_024448.2
	AK056875.1
	AK091837.1
	AK125808.1	1	1781
	BX538181.1
	CR933599.1	1	1814

Target Gene Details

• Entrez Gene ID: 266747
• Gene Name: ral guanine nucleotide dissociation stimulator like 4
• Gene Aliases: Rgr
• Location: Chr.22:23690861-23699176 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RGL4	NM_153615.1	1	512	NP_705843.1
	AK131340.1	3	950	BAD18497.1
	AY101396.1	1	512	AAM51551.1
	BC101108.3			AAI01109.1
	BC101109.2			AAI01110.1
	BC101110.3

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv8039n54	Chr.22:23323169 - 24601506 on Build GRCh38	Gain	VPREB3 LOC107985555 RGL4 LRRC75B IGLL1 DDTL MIF DERL3 DRICH1 LOC388882 GSTT2B GGT5 GUSBP11 SUSD2 C22orf15 GUCD1 DDT SNRPD3 SPECC1L ADORA2A-AS1 LOC101929374 LOC107985559 ZDHHC8P1 PCAT14 ZNF70 ADORA2A CABIN1 CHCHD10 SMARCB1 GSTT2 MIF-AS1 SLC2A11 LOC100652871 POM121L9P SPECC1L-ADORA2A CES5AP1 MMP11 GSTTP1 UPB1 GGT1
esv3893461	Chr.22:23509514 - 23995877 on Build GRCh38	Gain	VPREB3 LOC107985559 RGL4 PCAT14 IGLL1 ZNF70 CHCHD10 DDTL MIF SMARCB1 DERL3 GSTT2 DRICH1 GSTT2B MIF-AS1 SLC2A11 LOC100652871 GUSBP11 MMP11 C22orf15 DDT
esv2724041	Chr.22:23315914 - 24669376 on Build GRCh38	Deletion	VPREB3 LOC107985555 RGL4 LRRC75B IGLL1 DDTL MIF DERL3 DRICH1 LOC388882 GSTT2B GGT5 GUSBP11 SUSD2 C22orf15 GUCD1 DDT SNRPD3 SPECC1L ADORA2A-AS1 LOC101929374 LOC107985559 ZDHHC8P1 BCRP3 PCAT14 ZNF70 POM121L10P ADORA2A CABIN1 CHCHD10 BCR SMARCB1 GSTT2 MIF-AS1 SLC2A11 LOC100652871 POM121L9P SPECC1L-ADORA2A CES5AP1 MMP11 GSTTP1 UPB1 GGT1
nsv526567	Chr.22:23348138 - 24600663 on Build GRCh38	Gain	VPREB3 LOC107985555 RGL4 LRRC75B IGLL1 DDTL MIF DERL3 DRICH1 LOC388882 GSTT2B GGT5 GUSBP11 SUSD2 C22orf15 GUCD1 DDT SNRPD3 SPECC1L ADORA2A-AS1 LOC101929374 LOC107985559 ZDHHC8P1 PCAT14 ZNF70 ADORA2A CABIN1 CHCHD10 SMARCB1 GSTT2 MIF-AS1 SLC2A11 LOC100652871 POM121L9P SPECC1L-ADORA2A CES5AP1 MMP11 GSTTP1 UPB1 GGT1
nsv1062411	Chr.22:23407914 - 23922609 on Build GRCh38	Gain	VPREB3 RGL4 PCAT14 IGLL1 ZNF70 CHCHD10 MIF SMARCB1 DERL3 DRICH1 LOC388882 MIF-AS1 SLC2A11 GUSBP11 MMP11 C22orf15 LOC101929374
esv3893457	Chr.22:22657560 - 23995877 on Build GRCh38	Gain	VPREB3 LOC107985555 RGL4 IGLL1 MIR5571 DDTL MIF IGLV2-5 IGLV3-21 DERL3 DRICH1 LOC388882 GSTT2B GUSBP11 IGLV3-19 C22orf15 DDT IGLC1 GNAZ IGLJ3 LOC101929374 IGLV4-3 LOC107985559 ZDHHC8P1 PCAT14 ZNF70 RSPH14 RAB36 CHCHD10 BCR SMARCB1 IGLL5 GSTT2 MIF-AS1 SLC2A11 LOC100652871 CES5AP1 MIR650 MMP11 FBXW4P1 IGLV3-25
dgv4528n100	Chr.22:23322244 - 24682765 on Build GRCh38	Gain	VPREB3 LOC107985555 RGL4 LRRC75B IGLL1 DDTL MIF DERL3 DRICH1 LOC388882 GSTT2B GGT5 GUSBP11 SUSD2 C22orf15 GUCD1 DDT SNRPD3 SPECC1L ADORA2A-AS1 LOC101929374 LOC107985559 ZDHHC8P1 BCRP3 PCAT14 ZNF70 POM121L10P ADORA2A CABIN1 CHCHD10 SMARCB1 GSTT2 MIF-AS1 SLC2A11 LOC100652871 POM121L9P SPECC1L-ADORA2A CES5AP1 MMP11 GSTTP1 UPB1 GGT1
nsv1066891	Chr.22:22611045 - 24001082 on Build GRCh38	Gain	VPREB3 LOC107985555 RGL4 IGLL1 MIR5571 GGTLC2 DDTL MIF IGLV2-5 IGLV3-21 DERL3 DRICH1 LOC388882 GSTT2B GUSBP11 IGLV3-19 C22orf15 POM121L1P DDT IGLC1 GNAZ IGLJ3 LOC101929374 IGLV4-3 LOC107985559 ZDHHC8P1 PCAT14 ZNF70 RSPH14 RAB36 CHCHD10 BCR SMARCB1 IGLL5 GSTT2 MIF-AS1 SLC2A11 LOC100652871 CES5AP1 MIR650 MMP11 GSTTP1 FBXW4P1 IGLV3-25
esv3575443	Chr.22:23348201 - 24670505 on Build GRCh38	Gain	VPREB3 LOC107985555 RGL4 LRRC75B IGLL1 DDTL MIF DERL3 DRICH1 LOC388882 GSTT2B GGT5 GUSBP11 SUSD2 C22orf15 GUCD1 DDT SNRPD3 SPECC1L ADORA2A-AS1 LOC101929374 LOC107985559 ZDHHC8P1 BCRP3 PCAT14 ZNF70 POM121L10P ADORA2A CABIN1 CHCHD10 SMARCB1 GSTT2 MIF-AS1 SLC2A11 LOC100652871 POM121L9P SPECC1L-ADORA2A CES5AP1 MMP11 GSTTP1 UPB1 GGT1
esv2751941	Chr.22:23689828 - 23708284 on Build GRCh38	Gain	RGL4 GUSBP11

More Information

Additional Information:

For this assay, SNP(s) [rs151055453] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

small GTPase mediated signal transduction
positive regulation of GTPase activity

Function(s)

guanyl-nucleotide exchange factor activity