Hs00371034_cn

• Gene Symbol: SERGEF
• Assay Reference Genome Location: Chr.11:17788119 on build GRCh38
• Cytoband: 11p15.1

Target Gene Details

• Entrez Gene ID: 26297
• Gene Name: secretion regulating guanine nucleotide exchange factor
• Gene Aliases: DELGEF, Gnefr
• Location: Chr.11:17788048-18013162 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERGEF	NM_012139.3	11	1495	NP_036271.1
	NR_104040.1	12	1580
	NR_104041.1	10	1328
	AF086056.1	2	320
	AJ243950.1	11	1361	CAB60832.1
	AJ243951.1	10	1194	CAB60833.1
	AK292286.1	11	1495
	BC065375.1	11	1475	AAH65375.1
	CB051322.1	1	103

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv553589	Chr.11:17723445 - 17788177 on Build GRCh38	Loss	SERGEF KCNC1
nsv553567	Chr.11:16890704 - 17946708 on Build GRCh38	Gain	OTOG ABCC8 NUCB2 NCR3LG1 SNORD14B MYOD1 RPS13 USH1C PLEKHA7 SNORD14A SERGEF KCNJ11 LOC102723330 LOC105376575 OR7E14P PIK3C2A KCNC1
nsv509390	Chr.11:17726193 - 17855296 on Build GRCh38	Insertion	SERGEF KCNC1
nsv832078	Chr.11:17758956 - 17931974 on Build GRCh38	Loss	SERGEF KCNC1
nsv516767	Chr.11:17737040 - 17788177 on Build GRCh38	Loss	SERGEF KCNC1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

signal transduction
positive regulation of GTPase activity
negative regulation of protein secretion

Function(s)

Ran guanyl-nucleotide exchange factor activity
protein binding