Hs00393947_cn

• Gene Symbol: HDAC10
• Assay Reference Genome Location: Chr.22:50245686 on build GRCh38
• Cytoband: 22q13.33

Target Gene Details

• Entrez Gene ID: 83933
• Gene Name: histone deacetylase 10
• Gene Aliases: HD10
• Location: Chr.22:50245183-50251405 on Build GRCh38
• Assay Gene Location: Overlaps Intron 19 - Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HDAC10	NM_001159286.1			NP_001152758.1
	NM_032019.5			NP_114408.3
	AF393962.1			AAK84023.1
	AF407272.1			AAK92205.1
	AF407273.1			AAK92206.1
	AF426160.1			AAL30513.1
	AY450395.1			AAS48345.1
	BC125082.1
	BC125083.1
	BM983038.1
	CA424576.1
	CR456465.1			CAG30351.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv955199	Chr.22:50149372 - 50320271 on Build GRCh38	Deletion	DENND6B TUBGCP6 HDAC10 SELO MAPK11 PLXNB2 TRABD PANX2 MAPK12 MOV10L1
nsv471223	Chr.22:50190317 - 50271919 on Build GRCh38	Loss	TUBGCP6 HDAC10 SELO MAPK11 TRABD MAPK12
dgv781n67	Chr.22:50153213 - 50314433 on Build GRCh38	Gain	DENND6B TUBGCP6 HDAC10 SELO MAPK11 PLXNB2 TRABD PANX2 MAPK12 MOV10L1
nsv1066496	Chr.22:50226183 - 50292445 on Build GRCh38	Loss	TUBGCP6 HDAC10 MAPK11 PLXNB2 MAPK12

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
protein deacetylation
oligodendrocyte development
chromatin modification
histone deacetylation
negative regulation of transcription, DNA-templated
histone H3 deacetylation

Function(s)

histone deacetylase activity
protein binding
enzyme binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
histone deacetylase binding