Hs00405557_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143991776 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Overlaps Exon 3 - Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1			NP_000828.1
	NM_001009184.1			NP_001009184.1
	AB097026.1			BAC77379.1
	AK127640.1
	AK294127.1
	BC041788.1			AAH41788.2
	BC084553.1			AAH84553.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	GRINA PLEC PARP10
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	CYHR1 MIR6846 GPT PLEC HSF1 PPP1R16A SHARPIN MIR661 TONSL-AS1 MIR6848 RECQL4 WDR97 FOXH1 CYC1 MIR6847 MIR1234 LRRC14 LOC101928953 ADCK5 SMPD5 MIR6849 CPSF1 FBXL6 OPLAH SCX TONSL TMEM249 BOP1 VPS28 GRINA MFSD3 SLC52A2 MAF1 LOC101928902 EXOSC4 MROH1 SPATC1 SCRT1 KIFC2 DGAT1 MIR7112 MIR6893 GPAA1 HGH1 PARP10 MIR939 SLC39A4
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	CYHR1 MIR6846 GPT PLEC HSF1 PPP1R16A SHARPIN MIR661 TONSL-AS1 MIR6848 RECQL4 WDR97 FOXH1 CYC1 MIR6847 MIR1234 LRRC14 LOC101928953 ADCK5 SMPD5 MIR6849 CPSF1 FBXL6 OPLAH SCX TONSL TMEM249 BOP1 VPS28 GRINA MFSD3 SLC52A2 MAF1 LOC101928902 EXOSC4 MROH1 SPATC1 SCRT1 KIFC2 DGAT1 MIR7112 MIR6893 GPAA1 HGH1 PARP10 MIR939 SLC39A4
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	OPLAH MIR6846 GRINA MAF1 PLEC SHARPIN EXOSC4 SPATC1 WDR97 CYC1 MIR6847 GPAA1 PARP10 SMPD5
dgv906n27	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	OPLAH EPPK1 MIR6846 GRINA MAF1 PLEC SHARPIN EXOSC4 MROH1 SPATC1 MIR661 WDR97 CYC1 MIR6847 GPAA1 HGH1 PARP10 SMPD5
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	OPLAH EPPK1 MIR6846 GRINA MAF1 PLEC SHARPIN EXOSC4 SPATC1 MIR661 WDR97 CYC1 MIR6847 GPAA1 PARP10 SMPD5
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	OPLAH EPPK1 LOC642574 MIR6846 GRINA MIR6845 PLEC PUF60 EXOSC4 SPATC1 MIR661 MIR6847 NRBP2 SCRIB MIR937 PARP10 SMPD5
dgv12432n54	Chr.8:143902404 - 144007080 on Build GRCh38	Loss	GRINA PLEC PARP10 MIR661
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	OPLAH CYC1 MIR6847 MIR6846 GRINA PLEC GPAA1 PARP10 SMPD5 EXOSC4 SPATC1 MIR661
nsv612907	Chr.8:143917935 - 144097007 on Build GRCh38	Gain+Loss	OPLAH CYC1 MIR6847 MIR6846 GRINA PLEC GPAA1 PARP10 SMPD5 EXOSC4 SPATC1 MIR661

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding