Hs00409502_cn

• Gene Symbol: NOXA1
• Assay Reference Genome Location: Chr.9:137434246 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10811
• Gene Name: NADPH oxidase activator 1
• Gene Aliases: NY-CO-31, SDCCAG31, p51NOX
• Location: Chr.9:137423372-137434406 on Build GRCh38
• Assay Gene Location: Overlaps Intron 14 - Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOXA1	NM_001256067.1			NP_001242996.1
	NM_001256068.1			NP_001242997.1
	NM_006647.1			NP_006638.1
	XM_011518158.2			XP_011516460.1
	XM_011518159.1			XP_011516461.1
	XM_011518160.1			XP_011516462.1
	XM_017014220.1			XP_016869709.1
	AB095031.1			BAC76710.1
	AF039697.1			AAC18046.1
	AI860821.1
	AK098341.1
	AY255769.1			AAP13480.1
	AY927790.1			AAY16126.1
	AY927791.1			AAY16127.1
	BC041594.1			AAH41594.1
	BC110840.1			AAI10841.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1049808	Chr.9:137356366 - 137438026 on Build GRCh38	Gain	NOXA1 ENTPD8 EXD3
nsv951208	Chr.9:137379349 - 137467948 on Build GRCh38	Deletion	NOXA1 PNPLA7 ENTPD8 MIR7114 EXD3 NSMF
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	CCDC183-AS1 NPDC1 RABL6 TUBB4B LRRC26 CYSRT1 NELFB ABCA2 FBXW5 MAMDC4 NRARP ANAPC2 EXD3 UAP1L1 NOXA1 SSNA1 C9orf142 TOR4A C9orf172 ENTPD2 MIR4479 MAN1B1 DPP7 NDOR1 LCNL1 TMEM203 EDF1 TPRN SLC34A3 PNPLA7 ENTPD8 TRAF2 PHPT1 FAM166A MIR3621 RNF224 LCN12 LOC101930307 C9orf173-AS1 PRR31 MIR7114 GRIN1 CCDC183 C9orf139 PTGDS STPG3 CLIC3 MIR4292 FUT7 C8G MAN1B1-AS1 NSMF TMEM210 SAPCD2 RNF208
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	NOXA1 ENTPD8 EXD3
nsv6771	Chr.9:137412670 - 137444666 on Build GRCh38	Insertion	NOXA1 ENTPD8 EXD3
esv3622034	Chr.9:137433077 - 137439026 on Build GRCh38	Gain	NOXA1 ENTPD8
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	ANAPC2 C9orf173-AS1 NDOR1 TMEM203 EXD3 GRIN1 TUBB4B LRRC26 TPRN CYSRT1 SLC34A3 NOXA1 STPG3 SSNA1 ENTPD8 TOR4A NELFB FAM166A MIR3621 TMEM210 NRARP RNF224 RNF208

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator

Gene Ontology Categories:

Process(es)

superoxide metabolic process
regulation of hydrogen peroxide metabolic process
positive regulation of catalytic activity
regulation of respiratory burst

Function(s)

protein binding
superoxide-generating NADPH oxidase activator activity
SH3 domain binding
enzyme binding
Rac GTPase binding