Hs00419956_cn

• Gene Symbol: MXD4
• Assay Reference Genome Location: Chr.4:2247475 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 10608
• Gene Name: MAX dimerization protein 4
• Gene Aliases: MAD4, MST149, MSTP149, bHLHc12
• Location: Chr.4:2247432-2262143 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MXD4	NM_006454.2			NP_006445.1
	XM_011513388.2			XP_011511690.1
	AF082740.1			AAF98553.1
	AK026392.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv508990	Chr.4:2246239 - 2324327 on Build GRCh38	Insertion	ZFYVE28 MXD4 MIR4800
nsv593376	Chr.4:2246106 - 2251118 on Build GRCh38	Loss	MXD4 MIR4800
nsv1009347	Chr.4:2200935 - 2516063 on Build GRCh38	Gain	HAUS3 ZFYVE28 POLN RNF4 CFAP99 MXD4 MIR4800
esv2726835	Chr.4:2019561 - 2959568 on Build GRCh38	Deletion	ZFYVE28 FAM193A SH3BP2 NOP14-AS1 C4orf48 RNF4 MXD4 ADD1 MIR4800 MFSD10 HAUS3 NAT8L POLN CFAP99 TNIP2 NOP14
nsv593375	Chr.4:2243138 - 2251253 on Build GRCh38	Loss	MXD4 MIR4800
nsv829838	Chr.4:2155167 - 2349950 on Build GRCh38	Loss	HAUS3 ZFYVE28 POLN MXD4 MIR4800

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of cell proliferation

Function(s)

DNA binding
transcription corepressor activity
protein binding
protein dimerization activity