Hs00447103_cn

• Gene Symbol: LOC100288866
• Assay Reference Genome Location: Chr.17:49506560 on build GRCh38
• Cytoband: 17q21.33

Target Gene Details

• Entrez Gene ID: 100288866
• Gene Name: uncharacterized LOC100288866
• Gene Aliases: -
• Location: Chr.17:49505657-49574064 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC100288866	NR_103773.1
	AK303671.1

Target Gene Details

• Entrez Gene ID: 4804
• Gene Name: nerve growth factor receptor
• Gene Aliases: CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR
• Location: Chr.17:49495293-49515020 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NGFR	NM_002507.3	3	595	NP_002498.1
	AK303278.1	3	663
	AK313654.1	3	595
	BC050309.1	3	595	AAH50309.1
	DA115173.1
	M14764.1	3	583	AAB59544.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833473	Chr.17:49383665 - 49545926 on Build GRCh38	Gain+Loss	LOC100288866 LOC101927207 MIR6165 NGFR PHB

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

intracellular protein transport
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
immune response
axon guidance
response to wounding
negative regulation of neuron projection development
sensory perception of pain
membrane protein intracellular domain proteolysis
positive regulation of myelination
positive regulation of synaptic transmission, cholinergic
response to lipopolysaccharide
circadian regulation of gene expression
tumor necrosis factor-mediated signaling pathway
cellular response to oxidative stress
positive regulation of Rho protein signal transduction
skeletal muscle cell differentiation
regulation of cell proliferation
glucose homeostasis
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
neurotrophin TRK receptor signaling pathway
negative regulation of axonogenesis
positive regulation of axonogenesis
positive regulation of protein kinase B signaling
negative regulation of mitochondrial depolarization
positive regulation of synaptic transmission, glutamatergic
apoptotic signaling pathway
positive regulation of neuron death
regulation of reactive oxygen species metabolic process
regulation of glucose import in response to insulin stimulus

Function(s)

beta-amyloid binding
signal transducer activity
receptor activity
transmembrane signaling receptor activity
tumor necrosis factor-activated receptor activity
neurotrophin TRKA receptor binding
protein binding
Rab GTPase binding
ubiquitin protein ligase binding
nerve growth factor binding
preprotein binding