Hs00503195_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1074692 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Overlaps Exon 12 - Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2			NP_001245257.1
	NM_001282335.1			NP_001269264.1
	NM_001321232.1			NP_001308161.1
	NM_012292.4			NP_036424.2
	XM_006722713.1			XP_006722776.1
	XM_011527858.1			XP_011526160.1
	AK128097.1
	AK300341.1
	AK304271.1
	AK304765.1
	BC035564.1			AAH35564.1
	BC065223.1			AAH65223.1
	D86976.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	CIRBP POLR2E CBARP SBNO2 GPX4 EFNA2 ABCA7 MIDN STK11 ARHGAP45 CIRBP-AS1 LOC102725180 ATP5D C19orf24
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	GRIN3B RNU6-2 CIRBP LOC105372235 POLR2E RNU6-9 WDR18 CBARP SBNO2 CNN2 GPX4 R3HDM4 KISS1R ARID3A EFNA2 ABCA7 MIDN TMEM259 STK11 ARHGAP45 CIRBP-AS1 LOC102725180 ATP5D C19orf24
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	CIRBP POLR2E CBARP SBNO2 CNN2 GPX4 EFNA2 ABCA7 MIDN STK11 ARHGAP45 CIRBP-AS1 LOC102725180 ATP5D C19orf24
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	POLR2E WDR18 SBNO2 R3HDM4 TMEM259 MED16 STK11 ATP5D C19orf24 GRIN3B RNU6-2 CIRBP LOC105372235 RNU6-9 CBARP CNN2 GPX4 KISS1R ARID3A EFNA2 ABCA7 MIDN ARHGAP45 CIRBP-AS1 LOC102725180
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	GPX4 POLR2E ABCA7 SBNO2 ARHGAP45
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	GPX4 GRIN3B RNU6-2 LOC105372235 POLR2E ARID3A ABCA7 WDR18 TMEM259 SBNO2 CNN2 ARHGAP45
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	GPX4 GRIN3B RNU6-2 LOC105372235 POLR2E ARID3A ABCA7 WDR18 TMEM259 SBNO2 CNN2 ARHGAP45
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	PRSS57 POLR2E FSTL3 WDR18 C2CD4C MIR4745 FGF22 MIR3187 R3HDM4 ODF3L2 TMEM259 MED16 BSG AZU1 POLRMT GRIN3B SHC2 MADCAM1 PLPPR3 RNU6-2 LOC105372235 RNU6-9 CFD ELANE HCN2 LOC101928450 CNN2 GZMM MISP GPX4 THEG CDC34 PRTN3 KISS1R ARID3A ABCA7 RNF126 TPGS1 PTBP1 ARHGAP45 PALM
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	GPX4 RNU6-2 POLR2E ABCA7 TMEM259 SBNO2 CNN2 ARHGAP45

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding