Hs00512595_cn

• Gene Symbol: PAQR4
• Assay Reference Genome Location: Chr.16:2973442 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 124222
• Gene Name: progestin and adipoQ receptor family member 4
• Gene Aliases: -
• Location: Chr.16:2969245-2973489 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PAQR4	NM_001284511.1			NP_001271440.1
	NM_001284512.1			NP_001271441.1
	NM_001284513.1			NP_001271442.1
	NM_001324118.1			NP_001311047.1
	NM_152341.4			NP_689554.2
	AF086057.1
	AK054564.1			BAB70758.1
	AK092173.1			BAC03821.1
	AL832527.1
	BC033703.1			AAH33703.1
	BU739514.1

Target Gene Details

• Entrez Gene ID: 9088
• Gene Name: protein kinase, membrane associated tyrosine/threonine 1
• Gene Aliases: MYT1, PPP1R126
• Location: Chr.16:2972791-2980539 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PKMYT1	NM_001258450.1			NP_001245379.1
	NM_001258451.1			NP_001245380.1
	NM_004203.4			NP_004194.3
	NM_182687.2			NP_872629.1
	XM_011522734.2			XP_011521036.1
	XM_011522735.2			XP_011521037.1
	XM_011522736.2			XP_011521038.1
	AK097642.1
	AK098452.1
	AK294379.1
	AK301926.1
	AK303005.1
	AK309964.1
	BC121161.1
	BC121162.1
	BC130011.1
	BQ017689.1
	U56816.1			AAC50949.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv571246	Chr.16:2942113 - 2973604 on Build GRCh38	Loss	PAQR4 PKMYT1 FLYWCH1 KREMEN2
nsv509588	Chr.16:2919880 - 3043776 on Build GRCh38	Insertion	LINC00514 CLDN9 CLDN6 FLYWCH1 THOC6 PAQR4 HCFC1R1 LOC101929613 TNFRSF12A PKMYT1 LOC100128770 BICDL2 KREMEN2
nsv827525	Chr.16:2960856 - 2976333 on Build GRCh38	Gain	PAQR4 PKMYT1 KREMEN2
nsv952906	Chr.16:2868600 - 3028099 on Build GRCh38	Deletion	LINC00514 CLDN9 CLDN6 FLYWCH1 THOC6 FLYWCH2 PAQR4 HCFC1R1 LOC101929613 TNFRSF12A PKMYT1 BICDL2 KREMEN2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor, non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
protein phosphorylation
mitotic nuclear division
regulation of mitotic nuclear division
negative regulation of phosphatase activity
regulation of cell cycle

Function(s)

receptor activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
metal ion binding