Hs00523581_cn

• Gene Symbol: LOC105370757
• Assay Reference Genome Location: Chr.15:32670194 on build GRCh38
• Cytoband: 15q13.3

Target Gene Details

• Entrez Gene ID: 105370757
• Gene Name: uncharacterized LOC105370757
• Gene Aliases: -
• Location: Chr.15:32665702-32673065 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105370757	NR_135505.1
	BX088994.1

Target Gene Details

• Entrez Gene ID: 6447
• Gene Name: secretogranin V
• Gene Aliases: 7B2, P7B2, SGNE1, SgV
• Location: Chr.15:32641669-32697097 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SCG5	NM_001144757.1			NP_001138229.1
	NM_003020.3			NP_003011.1
	AK314965.1
	BC005349.1			AAH05349.1
	BC093053.1			AAH93053.1
	BP377248.1
	CR541824.1			CAG46623.1
	Y00757.1			CAA68726.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv568913	Chr.15:32633875 - 33060788 on Build GRCh38	Gain	LOC100131315 GREM1 FMN1 ARHGAP11A SCG5 LOC105370757
nsv428302	Chr.15:31646275 - 32694378 on Build GRCh38	Gain+Loss	LOC101060588 SCG5 OTUD7A GOLGA8N CHRNA7 LOC100653133 WHAMMP1 GOLGA8K GOLGA8O LOC101928042 ARHGAP11A ULK4P1 LOC105370940 LOC105370757 LOC100996255
esv2760023	Chr.15:31474097 - 32694378 on Build GRCh38	Gain+Loss	LOC101060588 SCG5 OTUD7A GOLGA8N CHRNA7 LOC100653133 WHAMMP1 GOLGA8K GOLGA8O LOC101928042 ARHGAP11A ULK4P1 LOC105370940 LOC105370757 LOC100996255
nsv1052620	Chr.15:32612402 - 34538731 on Build GRCh38	Gain	RYR3 SLC12A6 EMC4 EMC7 GREM1 FMN1 SCG5 LPCAT4 LOC101928134 NUTM1 AVEN GOLGA8B PGBD4 GOLGA8A LOC100131315 KATNBL1 LOC101928042 MIR1233-2 ARHGAP11A NOP10 MIR1233-1 TMCO5B LOC105370757 CHRM5
nsv483039	Chr.15:32574635 - 32751321 on Build GRCh38	Gain	LOC100131315 GREM1 LOC101928042 ARHGAP11A SCG5 GOLGA8N LOC105370757 LOC100996255
esv33337	Chr.15:31689863 - 34575097 on Build GRCh38	Gain+Loss	RYR3 EMC4 EMC7 GREM1 FMN1 LOC101060588 LPCAT4 LOC101928134 CHRNA7 NUTM1 AVEN WHAMMP1 LOC100131315 KATNBL1 LOC101928042 MIR1233-2 MIR1233-1 SLC12A6 SCG5 GOLGA8N GOLGA8B PGBD4 LOC100653133 GOLGA8A GOLGA8K GOLGA8O ARHGAP11A NOP10 ULK4P1 LOC105370940 TMCO5B LOC105370757 CHRM5 LOC100996255
esv3892661	Chr.15:32393132 - 32776080 on Build GRCh38	Gain	GREM1 FMN1 LOC101060588 SCG5 GOLGA8N LOC100653133 WHAMMP1 LOC100131315 GOLGA8K GOLGA8O LOC101928042 ARHGAP11A ULK4P1 LOC105370757 LOC100996255
nsv469587	Chr.15:32529739 - 32694378 on Build GRCh38	Loss	LOC101928042 ARHGAP11A SCG5 GOLGA8N LOC105370757 WHAMMP1 LOC100996255
esv2422296	Chr.15:32506737 - 32929014 on Build GRCh38	Duplication	LOC100131315 GREM1 LOC101928042 FMN1 ARHGAP11A SCG5 GOLGA8N LOC105370757 WHAMMP1 LOC100996255
dgv4456n54	Chr.15:32604149 - 34557061 on Build GRCh38	Gain	RYR3 EMC4 EMC7 GREM1 FMN1 LPCAT4 LOC101928134 NUTM1 AVEN LOC100131315 KATNBL1 LOC101928042 MIR1233-2 MIR1233-1 SLC12A6 SCG5 GOLGA8N GOLGA8B PGBD4 GOLGA8A ARHGAP11A NOP10 TMCO5B LOC105370757 CHRM5

More Information

Additional Information:

For this assay, SNP(s) [rs76845289] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

intracellular protein transport
neuropeptide signaling pathway
peptide hormone processing
negative regulation of catalytic activity
regulation of hormone secretion

Function(s)

enzyme inhibitor activity
protein binding
GTP binding
unfolded protein binding