Hs00531473_cn

• Gene Symbol: ADGRA2
• Assay Reference Genome Location: Chr.8:37843864 on build GRCh38
• Cytoband: 8p11.23

Target Gene Details

• Entrez Gene ID: 25960
• Gene Name: adhesion G protein-coupled receptor A2
• Gene Aliases: GPR124, TEM5
• Location: Chr.8:37796883-37843986 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADGRA2	NM_032777.9	19	5912	NP_116166.9
	XM_011544481.2	19	5981	XP_011542783.1
	XM_011544482.2	18	5909	XP_011542784.1
	XM_011544483.2	18	5822	XP_011542785.1
	AB040964.2	16	5238	BAA96055.2
	AF378755.1	19	5539	AAL11992.1
	AI346793.1	1	139
	AK027296.1	6	1952	BAB55022.1
	AK074099.2	19	5443
	AL110244.1	1	2533	CAB53694.1
	AL137610.1	1	1011
	AL832524.1	3	2979	CAD38629.1
	AL832959.1	12	4582	CAH56283.1
	BC146774.1	16	5238

Target Gene Details

• Entrez Gene ID: 55290
• Gene Name: BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
• Gene Aliases: BRFU, TFIIIB50
• Location: Chr.8:37843880-37849913 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BRF2	NM_018310.3			NP_060780.2
	AA496239.1
	AF130058.1			AAG35486.1
	AF206673.2			AAG35669.2
	AK001914.1			BAA91975.1
	BC010648.1			AAH10648.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509261	Chr.8:37767151 - 37881434 on Build GRCh38	Insertion	PROSC BRF2 ADGRA2 RAB11FIP1
nsv528598	Chr.8:37803553 - 37859603 on Build GRCh38	Loss	BRF2 ADGRA2 RAB11FIP1
nsv951126	Chr.8:37827983 - 37845682 on Build GRCh38	Deletion	BRF2 ADGRA2

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor, general transcription factor

Gene Ontology Categories:

Process(es)

sprouting angiogenesis
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
central nervous system development
positive regulation of endothelial cell migration
endothelial cell migration
regulation of angiogenesis
regulation of chemotaxis
regulation of establishment of blood-brain barrier
negative regulation of vascular endothelial growth factor signaling pathway
DNA-templated transcription, initiation
regulation of transcription, DNA-templated

Function(s)

G-protein coupled receptor activity
protein binding
zinc ion binding