Hs00581796_cn

• Gene Symbol: SMPDL3B
• Assay Reference Genome Location: Chr.1:27955742 on build GRCh38
• Cytoband: 1p35.3

Target Gene Details

• Entrez Gene ID: 27293
• Gene Name: sphingomyelin phosphodiesterase acid like 3B
• Gene Aliases: ASML3B
• Location: Chr.1:27934955-27959157 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SMPDL3B	NM_001009568.2	6	978	NP_001009568.1
	NM_001304579.1	6	1049	NP_001291508.1
	NM_014474.3	6	978	NP_055289.2
	XM_011541259.2	7	1068	XP_011539561.1
	XM_011541260.2	7	1703	XP_011539562.1
	AK293489.1	5	680
	AK293566.1	6	975
	AK301349.1	6	933
	AK316500.1	6	904
	BC014444.1	6	895	AAH14444.1
	BX389470.1	2	111
	Y08134.1	6	870	CAA69328.1

More Information

Additional Information:

For this assay, SNP(s) [rs74467253] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, non-DGV Variation

Panther Classification:

Molecular Function -

hydrolase, phosphodiesterase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

sphingomyelin catabolic process
inflammatory response
biological_process
negative regulation of toll-like receptor signaling pathway
innate immune response
membrane lipid catabolic process
negative regulation of inflammatory response

Function(s)

molecular_function
sphingomyelin phosphodiesterase activity
phosphoric diester hydrolase activity
hydrolase activity, acting on glycosyl bonds
metal ion binding