Hs00621678_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137180513 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	MAN1B1-AS1 TMEM210 NDOR1 LRRC26 DPP7 RNF224 TPRN ANAPC2 UAP1L1 MAN1B1 GRIN1 SSNA1 RNF208 CYSRT1 TMEM203 LOC101930307 MIR3621 SLC34A3
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	C9orf173-AS1 NDOR1 RNF224 TPRN ANAPC2 TOR4A STPG3 TUBB4B NELFB SSNA1 RNF208 CYSRT1 EXD3 TMEM203 SLC34A3 NRARP FAM166A
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	CCDC183 NSMF NPDC1 CCDC183-AS1 RNF208 EXD3 MIR7114 TMEM203 MIR3621 SLC34A3 LCNL1 C8G MAN1B1-AS1 TRAF2 LRRC26 C9orf172 RABL6 DPP7 CLIC3 MIR4292 TPRN TOR4A SSNA1 CYSRT1 LCN12 FBXW5 ENTPD2 NRARP ABCA2 FAM166A TMEM210 C9orf173-AS1 C9orf139 PNPLA7 RNF224 SAPCD2 ANAPC2 STPG3 TUBB4B MAN1B1 GRIN1 PHPT1 EDF1 MIR4479 FUT7 ENTPD8 NDOR1 PRR31 C9orf142 UAP1L1 NELFB MAMDC4 LOC101930307 PTGDS NOXA1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TMEM210 C9orf173-AS1 NDOR1 LRRC26 RNF224 TPRN ANAPC2 TOR4A STPG3 TUBB4B GRIN1 NELFB SSNA1 RNF208 CYSRT1 EXD3 TMEM203 MIR3621 SLC34A3 NRARP FAM166A
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TMEM210 C9orf173-AS1 NDOR1 LRRC26 RNF224 TPRN ANAPC2 TOR4A STPG3 TUBB4B GRIN1 NELFB SSNA1 RNF208 CYSRT1 EXD3 TMEM203 ENTPD8 NOXA1 MIR3621 SLC34A3 NRARP FAM166A
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	MAN1B1-AS1 TMEM210 C9orf139 LRRC26 DPP7 SAPCD2 ANAPC2 NPDC1 UAP1L1 MAN1B1 GRIN1 SSNA1 FUT7 LOC101930307 ENTPD2 MIR3621
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	CCDC183 NPDC1 CCDC183-AS1 RNF208 SNORA17B EXD3 TMEM203 TMEM141 MIR3621 SLC34A3 LCNL1 C8G FAM69B MAN1B1-AS1 TRAF2 LRRC26 C9orf172 LINC01451 RABL6 DPP7 CLIC3 MIR4292 TPRN TOR4A LOC100128593 SSNA1 LCN6 CYSRT1 LCN12 FBXW5 EGFL7 SNHG7 AGPAT2 SNORA17A ENTPD2 NRARP ABCA2 FAM166A LCN15 TMEM210 C9orf173-AS1 C9orf139 MIR126 RNF224 SAPCD2 ANAPC2 STPG3 TUBB4B MAN1B1 GRIN1 PHPT1 EDF1 MIR6722 MIR4479 FUT7 NDOR1 HSPC324 LCN10 PRR31 C9orf142 UAP1L1 NELFB MAMDC4 LOC101930307 PTGDS LCN8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity