Hs00621678_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137180513 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	UAP1L1 RNF208 TMEM203 MIR3621 TPRN NDOR1 ANAPC2 LRRC26 TMEM210 LOC101930307 DPP7 SLC34A3 GRIN1 CYSRT1 RNF224 MAN1B1-AS1 SSNA1 MAN1B1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	RNF208 TMEM203 TPRN NDOR1 NELFB ANAPC2 C9orf173-AS1 FAM166A EXD3 TUBB4B SLC34A3 TOR4A NRARP CYSRT1 STPG3 RNF224 SSNA1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	C9orf139 RNF208 MIR3621 NDOR1 ANAPC2 C9orf173-AS1 TMEM210 LOC101930307 C8G EXD3 SLC34A3 TOR4A SAPCD2 TRAF2 MIR4292 SSNA1 UAP1L1 EDF1 NOXA1 ENTPD8 LCNL1 MIR4479 C9orf172 LRRC26 MIR7114 PNPLA7 FBXW5 FUT7 DPP7 RABL6 GRIN1 PHPT1 STPG3 CLIC3 RNF224 TPRN TUBB4B ENTPD2 NSMF NRARP CYSRT1 LCN12 MAMDC4 MAN1B1-AS1 CCDC183 ABCA2 C9orf142 PRR31 TMEM203 NELFB PTGDS NPDC1 FAM166A CCDC183-AS1 MAN1B1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	RNF208 TMEM203 MIR3621 TPRN NDOR1 NELFB ANAPC2 LRRC26 C9orf173-AS1 TMEM210 FAM166A EXD3 TUBB4B SLC34A3 GRIN1 TOR4A NRARP CYSRT1 STPG3 RNF224 SSNA1
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	UAP1L1 C9orf139 MIR3621 ANAPC2 LRRC26 TMEM210 NPDC1 LOC101930307 FUT7 DPP7 ENTPD2 GRIN1 SAPCD2 MAN1B1-AS1 SSNA1 MAN1B1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	RNF208 NOXA1 TMEM203 MIR3621 TPRN NDOR1 ENTPD8 NELFB ANAPC2 LRRC26 C9orf173-AS1 TMEM210 FAM166A EXD3 TUBB4B SLC34A3 GRIN1 TOR4A NRARP CYSRT1 STPG3 RNF224 SSNA1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	C9orf139 RNF208 LCN15 MIR3621 NDOR1 ANAPC2 C9orf173-AS1 TMEM210 LOC101930307 C8G EXD3 SLC34A3 TOR4A SAPCD2 TRAF2 MIR4292 SSNA1 MIR126 UAP1L1 EDF1 MIR6722 SNHG7 LCNL1 LOC100128593 MIR4479 EGFL7 C9orf172 LRRC26 LINC01451 FAM69B FBXW5 FUT7 DPP7 RABL6 GRIN1 SNORA17A PHPT1 STPG3 CLIC3 RNF224 TPRN TUBB4B ENTPD2 NRARP CYSRT1 LCN12 MAMDC4 LCN6 MAN1B1-AS1 CCDC183 ABCA2 C9orf142 PRR31 TMEM141 TMEM203 NELFB SNORA17B PTGDS NPDC1 FAM166A LCN10 LCN8 HSPC324 CCDC183-AS1 MAN1B1 AGPAT2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity