Hs00632724_cn

• Gene Symbol: SDHC
• Assay Reference Genome Location: Chr.1:161364216 on build GRCh38
• Cytoband: 1q23.3

Target Gene Details

• Entrez Gene ID: 6391
• Gene Name: succinate dehydrogenase complex subunit C
• Gene Aliases: CYB560, CYBL, PGL3, QPS1, SDH3
• Location: Chr.1:161314376-161364751 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SDHC	NM_001035511.1	5	2159	NP_001030588.1
	NM_001035512.1	5	2221	NP_001030589.1
	NM_001035513.1	4	2164	NP_001030590.1
	NM_001278172.1	4	2057	NP_001265101.1
	NM_003001.3	6	2323	NP_002992.1
	NR_103459.1	7	2350

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1010776	Chr.1:161312594 - 161439428 on Build GRCh38	Gain	SDHC CFAP126

More Information

Additional Information:

For this assay, SNP(s) [rs115718047] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

dehydrogenase

Gene Ontology Categories:

Process(es)

tricarboxylic acid cycle
mitochondrial electron transport, succinate to ubiquinone
aerobic respiration
oxidation-reduction process

Function(s)

succinate dehydrogenase activity
electron carrier activity
heme binding
metal ion binding