Hs00652432_cn

• Gene Symbol: AMER3
• Assay Reference Genome Location: Chr.2:130762456 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 205147
• Gene Name: APC membrane recruitment protein 3
• Gene Aliases: FAM123C
• Location: Chr.2:130754475-130768134 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMER3	NM_001105193.1	2	558	NP_001098663.1
	NM_001105194.1	2	494	NP_001098664.1
	NM_001105195.1	2	491	NP_001098665.1
	NM_152698.2	2	574	NP_689911.2
	XM_011510793.2	2	1600	XP_011509095.1
	AK095696.1	2	538	BAC04612.1
	AK289525.1	2	643
	AK291424.1	2	538
	BC113445.1	2	451
	BC113447.1	2	451
	BC143806.1	2	448
	DA318919.1	2	482
	DA401709.1
	DA500900.1
	DA773233.1

Target Gene Details

• Entrez Gene ID: 653269
• Gene Name: POTE ankyrin domain family member I
• Gene Aliases: POTE2beta
• Location: Chr.2:130462245-131626428 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POTEI

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4074n100	Chr.2:130550793 - 131291209 on Build GRCh38	Gain	FAM168B ARHGEF4 GPR148 TISP43 POTEI POTEE CYP4F30P CFC1 AMER3 LOC440910 POTEJ PLEKHB2
dgv731e199	Chr.2:130678437 - 131300107 on Build GRCh38	Deletion	FAM168B ARHGEF4 GPR148 POTEI POTEE CYP4F30P AMER3 LOC440910 PLEKHB2
esv2670824	Chr.2:130625264 - 131605218 on Build GRCh38	Deletion	LINC01120 POTEI NOC2LP2 POTEE CYP4F30P AMER3 CCDC74A LOC150776 FAM168B MIR4784 MZT2A ARHGEF4 GPR148 TUBA3D WTH3DI POTEKP LOC440910 POTEJ PLEKHB2
esv3893337	Chr.2:130722838 - 131194387 on Build GRCh38	Loss	FAM168B ARHGEF4 GPR148 POTEI AMER3 PLEKHB2
dgv616e201	Chr.2:130674635 - 131312550 on Build GRCh38	Deletion	FAM168B ARHGEF4 GPR148 POTEI POTEE CYP4F30P AMER3 LOC440910 PLEKHB2
nsv583136	Chr.2:130730100 - 130846832 on Build GRCh38	Loss	ARHGEF4 GPR148 POTEI AMER3
nsv1014723	Chr.2:130720375 - 131379551 on Build GRCh38	Loss	FAM168B ARHGEF4 GPR148 POTEI POTEE WTH3DI AMER3 LOC440910 PLEKHB2
nsv583135	Chr.2:130724905 - 131194388 on Build GRCh38	Loss	FAM168B ARHGEF4 GPR148 POTEI AMER3 PLEKHB2
nsv524021	Chr.2:130724906 - 131553515 on Build GRCh38	Loss	LINC01120 POTEI NOC2LP2 POTEE AMER3 CCDC74A LOC150776 FAM168B MIR4784 MZT2A ARHGEF4 GPR148 TUBA3D WTH3DI LOC440910 PLEKHB2
esv2760576	Chr.2:130634172 - 131521752 on Build GRCh38	Gain+Loss	LINC01120 POTEI NOC2LP2 POTEE CYP4F30P AMER3 LOC150776 FAM168B MIR4784 MZT2A ARHGEF4 GPR148 TUBA3D WTH3DI LOC440910 POTEJ PLEKHB2
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	CCDC115 ANKRD30BL POTEI LOC100507460 TUBA3E POTEF MIR4784 FAM201B MIR663B C2orf27B FAR2P2 WTH3DI IMP4 LINC01120 FAR2P1 TISP43 NOC2LP2 LINC01087 CCDC74A CCDC74B SMPD4 FAM168B ARHGEF4 POTEKP ZNF806 GPR39 LOC101927924 POTEE MZT2B AMER3 MZT2A GPR148 RAB6C TUBA3D LOC389033 PTPN18 LOC440910 POTEJ NOC2LP1 CFC1B MED15P9 C2orf27A RAB6C-AS1 CYP4F30P LOC150776 LOC646743 CYP4F62P LOC107985778 CFC1 PLEKHB2
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CCDC115 LOC101927924 POTEI MZT2B AMER3 TUBA3E POTEF GPR148 RAB6C FAR2P2 LOC389033 IMP4 PTPN18 POTEJ NOC2LP1 CFC1B MED15P9 FAR2P1 TISP43 RAB6C-AS1 CYP4F30P CCDC74B LOC646743 SMPD4 CYP4F62P ARHGEF4 LOC107985778 CFC1

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

Wnt signaling pathway
anatomical structure development
regulation of canonical Wnt signaling pathway

Function(s)

protein binding
phosphatidylinositol-4,5-bisphosphate binding
beta-catenin binding