Hs00656216_cn

• Gene Symbol: PPP1R13L
• Assay Reference Genome Location: Chr.19:45380038 on build GRCh38
• Cytoband: 19q13.32

Target Gene Details

• Entrez Gene ID: 10848
• Gene Name: protein phosphatase 1 regulatory subunit 13 like
• Gene Aliases: IASPP, NKIP1, RAI, RAI4
• Location: Chr.19:45379634-45406349 on Build GRCh38
• Assay Gene Location: Within Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R13L	NM_001142502.1	13	2718	NP_001135974.1
	NM_006663.3	13	2716	NP_006654.2
	XM_017026177.1	14	2774	XP_016881666.1
	XM_017026178.1	14	2834	XP_016881667.1
	AF078036.1	7	1697	AAD27004.1
	AF078037.1	6	2151	AAD27005.1
	AY869712.1	13	2697	AAW51146.1
	BC001475.2	7	1303	AAH01475.1
	BC020589.1	6	957	AAH20589.1
	BC032298.1	13	2705	AAH32298.1
	BC064913.1	13	2681	AAH64913.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833845	Chr.19:45308814 - 45457371 on Build GRCh38	Loss	KLC3 ERCC2 CKM PPP1R13L MIR6088 CD3EAP ERCC1
esv3644502	Chr.19:45323147 - 45403933 on Build GRCh38	Gain	KLC3 ERCC2 PPP1R13L
dgv1054e212	Chr.19:45347119 - 45407663 on Build GRCh38	Gain	KLC3 ERCC2 PPP1R13L CD3EAP ERCC1
nsv458711	Chr.19:45323108 - 45408744 on Build GRCh38	Gain	KLC3 ERCC2 PPP1R13L CD3EAP ERCC1
nsv1063547	Chr.19:45322368 - 45400204 on Build GRCh38	Gain	KLC3 ERCC2 CKM PPP1R13L
dgv3606n100	Chr.19:45347435 - 45400204 on Build GRCh38	Gain	KLC3 ERCC2 PPP1R13L
nsv833844	Chr.19:45181051 - 45384148 on Build GRCh38	Loss	MARK4 KLC3 ERCC2 CKM PPP1R13L BLOC1S3 EXOC3L2
nsv428365	Chr.19:45358027 - 45469089 on Build GRCh38	Gain+Loss	ERCC2 FOSB PPP1R13L MIR6088 CD3EAP ERCC1
nsv442466	Chr.19:45347447 - 45388666 on Build GRCh38	Gain	KLC3 ERCC2 PPP1R13L

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cardiac right ventricle morphogenesis
ventricular cardiac muscle tissue development
transcription, DNA-templated
apoptotic process
post-embryonic development
embryonic camera-type eye development
multicellular organism growth
hair cycle
positive regulation of cell differentiation
multicellular organismal homeostasis
cardiac muscle contraction
cell-cell adhesion
regulation of signal transduction by p53 class mediator

Function(s)

transcription corepressor activity
protein binding
transcription factor binding
identical protein binding
cadherin binding involved in cell-cell adhesion