Hs00659955_cn

• Gene Symbol: PDE4C
• Assay Reference Genome Location: Chr.19:18211187 on build GRCh38
• Cytoband: 19p13.11

Target Gene Details

• Entrez Gene ID: 5143
• Gene Name: phosphodiesterase 4C
• Gene Aliases: DPDE1
• Location: Chr.19:18207961-18248200 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDE4C	NM_000923.4	16	2120	NP_000914.2
	NM_001098818.2	15	1845	NP_001092288.1
	NM_001098819.2	15	1898	NP_001092289.1
	NR_040546.1	14	1795
	XM_011528056.2	15	1851	XP_011526358.1
	XM_011528058.2	13	1427	XP_011526360.1
	XM_017026866.1	16	2129	XP_016882355.1
	AK295050.1	15	2361
	AK300983.1	15	1808
	BC109067.1	11	1343	AAI09068.1
	BC109068.2	12	1393	AAI09069.1
	L20968.1	4	505	AAA03591.1
	U66346.1	16	2120	AAB96875.1
	U66347.1	13	2876	AAB96876.1
	U66348.1	10	1301	AAB96877.1
	U66349.1	9	1026	AAB96878.1
	U88712.1	15	1898	AAC51915.1
	U88713.1	15	1845	AAC51916.1
	Z46632.1	15	1992	CAA86601.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952420	Chr.19:18117791 - 18476990 on Build GRCh38	Deletion	MAST3 RAB3A LOC102725254 LRRC25 GDF15 JUND MIR3189 ELL MIR3188 PGPEP1 LSM4 LOC729966 IFI30 SSBP4 PDE4C PIK3R2 MPV17L2 KIAA1683 ISYNA1
nsv833775	Chr.19:18102951 - 18279264 on Build GRCh38	Loss	MAST3 RAB3A LOC102725254 LOC729966 IFI30 PDE4C PIK3R2 MPV17L2 KIAA1683

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

cAMP catabolic process
signal transduction
negative regulation of insulin secretion

Function(s)

3',5'-cyclic-AMP phosphodiesterase activity
drug binding
metal ion binding