Hs00666958_cn

• Gene Symbol: LOC100289580
• Assay Reference Genome Location: Chr.16:88739734 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 100289580
• Gene Name: uncharacterized LOC100289580
• Gene Aliases: -
• Location: Chr.16:88731180-88741425 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC100289580	NR_103774.1	3	2085
	AK127064.1	2	2837

Target Gene Details

• Entrez Gene ID: 9780
• Gene Name: piezo type mechanosensitive ion channel component 1
• Gene Aliases: DHS, FAM38A, LMPH3, Mib
• Location: Chr.16:88715338-88785220 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIEZO1	NM_001142864.3			NP_001136336.2
	DR731297.1
	KC602455.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	CDH15 LOC107987238 PABPN1L CTU2 LOC105371409 MIR4722 APRT LINC00304 CDT1 LOC400558 GALNS LOC100289580 LOC339059 ACSF3 ZNF778 LOC100129697 TRAPPC2L CBFA2T3 PIEZO1 SLC22A31 LOC101927793
nsv471113	Chr.16:88650665 - 88764428 on Build GRCh38	Loss	MVD RNF166 CTU2 SNAI3-AS1 MIR4722 CYBA LOC100289580 LOC339059 SNAI3 PIEZO1
nsv471114	Chr.16:88688461 - 88756339 on Build GRCh38	Gain	RNF166 CTU2 MIR4722 LOC100289580 LOC339059 PIEZO1
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	RNF166 LOC107987238 CTU2 SNAI3-AS1 MIR4722 APRT CDT1 GALNS LOC100289580 LOC339059 SNAI3 PIEZO1
nsv517643	Chr.16:88713767 - 88756339 on Build GRCh38	Loss	CTU2 MIR4722 LOC100289580 LOC339059 PIEZO1
nsv833327	Chr.16:88667431 - 88757621 on Build GRCh38	Loss	RNF166 CTU2 SNAI3-AS1 MIR4722 LOC100289580 LOC339059 SNAI3 PIEZO1
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	CDH15 LOC107987238 PABPN1L LOC105371409 ANKRD11 APRT LINC00304 CDT1 LOC400558 GALNS LOC100289580 LOC339059 ACSF3 ZNF778 LOC100129697 LOC100287036 TRAPPC2L CBFA2T3 LOC105371414 PIEZO1 SLC22A31 LOC101927793
nsv952070	Chr.16:88257295 - 88780192 on Build GRCh38	Deletion	MIR5189 CTU2 ZC3H18-AS1 MIR4722 ZFPM1 LOC100289580 LOC339059 IL17C MVD RNF166 SNAI3-AS1 CYBA ZNF469 LOC107984862 ZC3H18 SNAI3 PIEZO1
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	CDH15 TUBB3 TCF25 SNORD68 VPS9D1-AS1 PRDM7 APRT RPL13 LOC400558 GAS8-AS1 FAM157C DPEP1 SPATA33 LOC100287036 LOC105371414 DBNDD1 SNAI3 CDK10 PIEZO1 LOC107987238 ANKRD11 GALNS ZNF778 SNAI3-AS1 MC1R LOC100129697 AFG3L1P CBFA2T3 GAS8 CTU2 LOC105371409 CHMP1A VPS9D1 MIR4722 LINC00304 CENPBD1 LOC339059 LOC105371419 ACSF3 RNF166 CYBA LOC107984817 PABPN1L CDT1 ZNF276 SPIRE2 CPNE7 LOC100289580 IL17C DEF8 MVD LOC101927817 TUBB8P7 FANCA SPG7 TRAPPC2L SPATA2L URAHP SLC22A31 LOC101927793
nsv1160442	Chr.16:88708161 - 88778524 on Build GRCh38	Deletion	CTU2 MIR4722 LOC100289580 LOC339059 PIEZO1
nsv1927	Chr.16:88712585 - 88743583 on Build GRCh38	Insertion	CTU2 MIR4722 LOC100289580 LOC339059 PIEZO1
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	LOC107987238 PABPN1L CTU2 LOC105371409 MIR4722 APRT CDT1 GALNS LOC100289580 LOC339059 LOC100129697 TRAPPC2L CBFA2T3 PIEZO1 LOC101927793

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cation transport
positive regulation of integrin activation
positive regulation of cell-cell adhesion mediated by integrin
cation transmembrane transport

Function(s)

cation channel activity
mechanically-gated ion channel activity